Clinical Research Laboratory Technician

5 days ago


Nottingham, Nottingham, United Kingdom Nottingham University Hospitals NHS Trusts Full time
About the Role

We are seeking an experienced Clinical Research Laboratory Technician to join our Research and Innovation department at Nottingham University Hospitals NHS Trusts. As a key member of our team, you will play a vital role in supporting the delivery of our Cell and Therapy services, including the processing and quality control testing of cellular material.

Key Responsibilities
  • Perform laboratory analyses and procedures associated with the post, including reporting results and maintaining appropriate records and documentation.
  • Undertake flow cytometry and support the interpretation of results.
  • Undertake storage, delivery, and shipping duties of cells.
  • Support quality control procedures, examine quality control results to identify poor performance.
  • Undertake routine and complex laboratory-based work such as the pre-analytical processing of clinical trial specimens and samples for analysis using various technologies.
  • Perform clerical tasks including, monitoring and querying sample processing requests made by the clinical team, completing sample tracking logs, equipment maintenance logs, and other documentations appropriate for the role.
  • Accurately follow, or in some cases design, protocols to ensure the smooth running of the facility and the accurate processing of study samples.
  • Collect, catalogue and store human tissue, blood and urine samples from within the R&I department, Nottingham University Hospitals or external sites. Manage sample storage facilities and maintain collections - this will involve monitoring freezers.
  • Organise sample retrieval from external sites. From time to time, some of this work may be out of hours therefore some flexibility within working hours is essential.
  • Culture of epithelial and smooth muscle cells from human lung biopsies.
  • Process human sputum samples including differential cell count.
  • To accurately record sample transfers both in and out of R&I laboratories.
  • Isolate stored samples for transfer to or from the R&I laboratories, this will involve arranging couriers and ensuring samples are packed appropriately.
  • Observe all GLP, GCP, HSE and HTA regulations. Maintain records to comply with Human Tissue Act, including assisting with sample audits. To adhere to Trust policy and procedures.
  • Be responsible for the upkeep of the lab areas and equipment. Maintain laboratory stock levels of chemicals and consumables and ensure adequate equipment maintenance.
  • Maintain and clean laboratory equipment and maintain a high standard of housekeeping within the laboratory.
  • Any other duties appropriate to the role and level.
  • To assist in the induction, and training of new laboratory staff, providing mentorship and support within the clinical team.
  • To contribute to the development of clinical and research policies, and Standard Operating procedures.
  • To act as a resource for colleagues in relation to clinical studies.
  • To attend relevant training and to gain experience from other laboratories. This may mean some travel is involved.
  • To keep appropriate staff informed of the progress of clinical studies.
  • To maintain an up-to-date knowledge of relevant research related articles particularly related to clinical studies.
  • To continue your own professional development according to appropriate regulatory guidance, keeping updated with current practice.
  • To assist with training of placement students in relevant scientific techniques
  • To attend national meetings/conferences in relation to clinical studies as appropriate and agreed with R&I Laboratory Manager


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