Research Assistant or Associate in Computational Genomics

2 weeks ago

London, Greater London, United Kingdom Imperial College London Full time

Research Opportunity

We are seeking a highly motivated Research Assistant or Associate in Computational Genomics to join our team at Imperial College London. The successful candidate will be responsible for leading one or more projects characterizing the relationship between brain and blood cell types to interpret Parkinson's disease susceptibility and its various clinical presentations.

Key Responsibilities

  • Lead one or more projects characterizing the relationship between brain and blood cell types to interpret Parkinson's disease susceptibility and its various clinical presentations.
  • Collaborate closely with Dr. Nathan Skene's group, which focuses on identifying the cell types and intracellular processes affected by the genetic loci underlying neurodegenerative diseases.
  • Analyse large-scale 'omics datasets, with a primary focus on the analysis of cellular architecture to address major research questions related to Parkinson's disease.
  • Work with next-generation sequencing data from patient-derived brain tissue and blood to identify cells and signalling pathways dysregulated in Parkinson's disease.

Requirements

  • Relevant MSc in Bioinformatics, Computational Biology, Mathematics, or a closely related discipline, or possess equivalent research, industrial, or commercial experience.
  • Practical experience within a research environment and/or publication in relevant and refereed journals.
  • Experience with high-performance computing environments.
  • Proficiency with a broad range of bioinformatics tools and databases.
  • Background knowledge of neuroscience, biological sciences, or a closely related discipline.
  • Background knowledge of the immune system.

What We Offer

  • Opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity.
  • Growth opportunities: Gain access to Imperial's sector-leading dedicated career support for researchers as well as opportunities for promotion and progression.
  • Sector-leading salary and remuneration package (including 39 days off a year and generous pension schemes).

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