Molecular Modeller Expert

6 days ago


Cambridge, Cambridgeshire, United Kingdom Reed Engineering Full time

About the Opportunity

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We are offering a challenging and rewarding role as a Computational Chemist at Reed Engineering, a dynamic Biotech company based in Cambridge. In this role, you will have the opportunity to work on cutting-edge drug discovery projects, using your expertise in computational chemistry, biomolecular structural analysis, and computational modelling techniques.

Your key responsibilities will include:

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  1. ">
  2. Leading computational chemistry support for multiple projects.">
  3. Collaborating with computational chemists, medicinal chemists, informaticians, and project teams.">
  4. Analysing and reporting on biomolecular and structural data using advanced modelling techniques.">
  5. Developing and delivering structure- and ligand-based models (e.g., pharmacophore, docking) to advance projects.">
  6. Applying a wide range of computer-aided drug design techniques.">
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To be successful in this role, you will require:

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  • ">
  • A PhD or equivalent in Computational Chemistry or a related field.">
  • Extensive experience in computer-aided drug discovery within pharma or biotech.">
  • Demonstrable knowledge of a wide range of computational chemistry approaches and their application to drug discovery.">
  • Practical experience in developing, deploying, and applying structure-based modelling techniques (e.g., docking, covalent docking, molecular dynamics simulations, FEP analysis).">
  • Experience with computer-aided drug design techniques (e.g., compound library design, virtual screening and pharmacophore modelling).">
  • A proven track record of innovation in computational chemistry and cheminformatics, evidenced by publications, presentations, or contributions to open-source projects.">
  • Experience using computational techniques (e.g., protein-protein docking, molecular dynamics).">
  • Familiarity with QM/MM techniques for geometry optimization, partial charge calculation, and frontier orbital visualization.">
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The estimated salary for this role is £60,000 - £80,000 per annum, depending on experience. If you possess the relevant skills and experience, we encourage you to apply for this exciting opportunity.



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