PhD Studentship in Human Lung Organoid Platform for Oncology

3 weeks ago


Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full time
Job Description

We are seeking a highly motivated and enthusiastic individual to join our team as a PhD student in the Department of Physiology, Development and Neuroscience at the University of Cambridge. The successful candidate will work on a collaborative project jointly supervised by Prof Emma Rawlins and Dr Luigi Aloia, and will have the opportunity to work across the two sites.

Project Overview

The project, entitled 'A reproducible human lung organoid platform for large scale oncology CRISPR screens', aims to develop a human-relevant model for studying lung cancer. The student will work on developing human lung adenocarcinoma from multiple normal biological donors, and will use genetic engineering to test the effects of cancer driver mutations.

Key Responsibilities
  • Conduct research in the field of human organoid/cancer biology
  • Develop and maintain human lung organoid cultures
  • Perform genetic engineering to develop human lung adenocarcinoma from multiple normal biological donors
  • Collaborate with the supervisory team to design and implement experiments
Requirements

We are looking for a candidate with a strong background in cell or developmental biology, or biochemistry. The successful candidate will have, or shortly expect to obtain, a first or upper second-class degree from a UK university, or an equivalent standard from an overseas university. The candidate should also have excellent communication and teamwork skills.

What We Offer

The studentship provides full funding covering maintenance fees and the University Composition Fee. The student will also have access to a wide range of training opportunities and benefit from close supervision provided by a primary and secondary PhD supervisor, as well as a personal mentor. Additionally, this studentship will involve regular interactions with mentors at AZ, and periods of working at AZ.

How to Apply

Applications should include a CV, transcript, two academic references, and a statement of interest outlining the candidate's suitability for the project and their background and research interests. The application deadline is 23:59pm UK time on Mon 11th November 2024.



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