Senior Bioinformatics Specialist

7 days ago


London, Greater London, United Kingdom Northreach Full time
About the Opportunity

Northreach is seeking an experienced Senior Bioinformatician/Data Scientist to drive research and development in gene-editing systems and mobile genetic elements.

The successful candidate will lead efforts focused on discovering, developing, and curating novel gene-editing mechanisms, applying advanced bioinformatics methods to catalog and characterize diverse gene-editing systems, and identifying therapeutic potential.

Key Responsibilities:

  • Lead research and curation efforts focused on gene-editing systems, moving beyond CRISPR screening to identify and annotate novel gene-editing mechanisms.
  • Apply advanced bioinformatics methods to catalog and characterize diverse gene-editing systems, with a focus on their therapeutic potential.
  • Identify, curate, and analyze MGEs and viral integration events within metagenomic datasets.
  • Develop methods to track and characterize these elements, enhancing understanding of their roles in gene mobility, genomic instability, and therapeutic applications.
  • Conduct comprehensive analyses on large metagenomic and microbiome datasets, utilizing robust computational tools to process and interpret complex data.
  • Generate insights into the microbial ecology, gene function, and genomic context of potential therapeutic elements within microbial communities.
  • Drive research with a therapeutic focus, identifying gene-editing systems or MGEs that can potentially be harnessed for human health applications.
  • Collaborate with interdisciplinary teams to translate findings from metagenomic and gene-editing studies into viable therapeutic candidates.


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