Population Genetics Expert

6 days ago


Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom Newcastle University Full time

About the Role

We are seeking a Population Genetics Expert to join our research team at Newcastle University. The successful candidate will be responsible for performing large-scale genetic analyses on patient cohort data to define nuclear determinants of mitochondrial DNA disease phenotypes.

The ideal candidate will have knowledge and experience of applying statistical genetic techniques such as GWAS, LMM etc. They will also have experience of working within a Unix/Linux HPC or cloud computing environment and competence in at least one (statistical) programming language, such as R, python etc.

Responsibilities

  • Perform large-scale genetic analyses on patient cohort data to define nuclear determinants of mitochondrial DNA disease phenotypes
  • Perform quality control and data harmonisation for clinical, genetic and environmental data across mitochondrial disease patient cohorts
  • Identify individuals who carry mtDNA mutations in large population cohorts such as UK Biobank and 100K Genomes Project and perform large-scale analysis of genetic, phenotypic, environmental and other relevant data within these cohorts

Requirements

  • Knowledge and experience of applying statistical genetic techniques such as GWAS, LMM etc
  • Experience of working within a Unix/Linux HPC or cloud computing environment
  • Competence in at least one (statistical) programming language, such as R, python etc
  • High-level analytical ability with attention to detail
  • Ability to work well as part of a team and rapidly acquire new skills

About the Location

Newcastle University is located in the heart of Newcastle Upon Tyne, with fantastic transport links and state-of-the-art facilities.

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