Genetic Data Analyst
4 days ago
About the Team
Our research team at Newcastle University is dedicated to advancing our understanding of mitochondrial biology and developing new therapies for patients and families. We are a vibrant, multi-disciplinary team working on well-characterised patient and large population cohorts.
We are looking for a motivated Genetic Data Analyst to join our team, backed by significant funding from a recently awarded Wellcome Career Development Award. This is an exciting opportunity to be part of a team at the forefront of pioneering research from the very start of a project.
The successful candidate will be responsible for performing large-scale genetic analyses on patient cohort data to define nuclear determinants of mitochondrial DNA disease phenotypes.
Key Responsibilities
- Perform large-scale genetic analyses on patient cohort data to define nuclear determinants of mitochondrial DNA disease phenotypes
- Perform quality control and data harmonisation for clinical, genetic and environmental data across mitochondrial disease patient cohorts
- Identify individuals who carry mtDNA mutations in large population cohorts such as UK Biobank and 100K Genomes Project and perform large-scale analysis of genetic, phenotypic, environmental and other relevant data within these cohorts
- Collect and collate environmental data from patients and their families through the use of questionnaires, with support
Requirements
- Knowledge and experience of applying statistical genetic techniques such as GWAS, LMM etc
- Experience of working within a Unix/Linux HPC or cloud computing environment
- Competence in at least one (statistical) programming language, such as R, python etc
- High-level analytical ability with attention to detail
- Ability to work well as part of a team and rapidly acquire new skills
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