Genetic Data Analyst

4 days ago


Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom Newcastle University Full time

About the Team

Our research team at Newcastle University is dedicated to advancing our understanding of mitochondrial biology and developing new therapies for patients and families. We are a vibrant, multi-disciplinary team working on well-characterised patient and large population cohorts.

We are looking for a motivated Genetic Data Analyst to join our team, backed by significant funding from a recently awarded Wellcome Career Development Award. This is an exciting opportunity to be part of a team at the forefront of pioneering research from the very start of a project.

The successful candidate will be responsible for performing large-scale genetic analyses on patient cohort data to define nuclear determinants of mitochondrial DNA disease phenotypes.

Key Responsibilities

  • Perform large-scale genetic analyses on patient cohort data to define nuclear determinants of mitochondrial DNA disease phenotypes
  • Perform quality control and data harmonisation for clinical, genetic and environmental data across mitochondrial disease patient cohorts
  • Identify individuals who carry mtDNA mutations in large population cohorts such as UK Biobank and 100K Genomes Project and perform large-scale analysis of genetic, phenotypic, environmental and other relevant data within these cohorts
  • Collect and collate environmental data from patients and their families through the use of questionnaires, with support

Requirements

  • Knowledge and experience of applying statistical genetic techniques such as GWAS, LMM etc
  • Experience of working within a Unix/Linux HPC or cloud computing environment
  • Competence in at least one (statistical) programming language, such as R, python etc
  • High-level analytical ability with attention to detail
  • Ability to work well as part of a team and rapidly acquire new skills


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