Research Scientist
4 days ago
Are you a highly motivated researcher looking to advance your career in molecular biology? We have an exciting opportunity for a Postdoctoral Research Associate at the University of York.
About the RoleWe are seeking a skilled researcher to join our team and contribute to a project investigating the signalling pathways that regulate autophagy, lysosome exocytosis, and biomolecular condensates during the lifecycle differentiations and host adaptation of the African trypanosome T. brucei.
The successful candidate will be responsible for validating a high-throughput live imaging system combined with gene silencing screens of protein kinases, as well as performing autophagy-related proximity labelling, phospho-proteomic, and mass spectrometry analysis.
The post requires a PhD in Molecular Biology, Cell Biology, or Microbiology, and knowledge of standard molecular biology techniques, -omics studies, and imaging techniques. Experience in handling murine models and pathogens, protein kinases, -omics data analysis, super-resolution microscopy, live imaging, and CRISPR/Cas9-mediated precision editing is highly desirable.
Key Responsibilities- Validate high-throughput live imaging system combined with gene silencing screen of protein kinases
- Autophagy-related proximity labelling, phospho-proteomic, and mass spectrometry analysis
- Assays of protein interaction and enzyme activity using biophysical and biochemical approaches
- Generation of mutated cell lines by CRISPR/Cas9-mediated precision editing and phenotypic validation in vitro and in murine model
- Biomolecular condensate purification and component analysis by mass spectrometry and sequencing
- PhD in Molecular Biology, Cell Biology, or Microbiology
- Knowledge of molecular biology, parasitology, and modern techniques
- Skills and experiences in cell culture, handling of class 2 pathogens, murine infection, and gene editing
- Excellent track record of research publications and developed communication skills
- Attention to detail, collaborative ethos, and willingness to work proactively
We offer a competitive salary of £32,000 - £38,000 per annum, depending on experience, as well as excellent benefits including family-friendly, flexible working arrangements, and inclusive facilities.
-
York, York City, United Kingdom Professor Doctor Obi Full timeJob OverviewWe are seeking a highly motivated Research Scientist to join our team at Professor Doctor Obi. This is an exciting opportunity for someone with a strong background in computational chemistry to contribute to cutting-edge research projects.
-
York, York City, United Kingdom University of York Full timeRole SummaryThis is an exciting opportunity to work as a Research Scientist at the University of York, contributing to the development of a web browser version of the protein editing and validation program Coot.About the RoleWe are seeking a highly motivated and skilled individual to join our team as a Research Scientist. The successful candidate will be...
-
Research Scientist in Bioimage Analysis
4 weeks ago
York, York City, United Kingdom University of York Full timeRoleWe are seeking a highly skilled Research Scientist to join our team at the University of York. The successful candidate will be responsible for developing and applying advanced bioimage analysis techniques to understand and predict cell behaviour in heterogeneous populations.Key ResponsibilitiesDevelop and apply machine learning algorithms to analyse...
-
Research Scientist in Bioimage Analysis
4 weeks ago
York, York City, United Kingdom University of York Full timeAbout the RoleWe are seeking a highly motivated Research Scientist to join our team at the University of York, working on advanced live cell imaging microscopy approaches and machine learning to understand and predict cell behaviour in heterogeneous populations. The successful candidate will have a PhD in a biomedical sciences discipline or equivalent...
-
Research Scientist
4 weeks ago
York, York City, United Kingdom University of York Full timeJob RoleThe University of York is seeking a highly skilled Research Associate to contribute to its research in laser-plasma interactions and strong-field physics. The successful candidate will be expected to perform high-impact research, provide support for experiments, and develop simulation tools for the community.Key ResponsibilitiesConduct research in...
-
Principal Research Scientist
2 weeks ago
York, York City, United Kingdom Bionow Full timeAbout the RoleWe are seeking an experienced Principal Research Scientist - Bioanalytical Team Lead to join our team at Bionow.This is a unique opportunity for a highly skilled and motivated individual to lead our bioanalytical team and contribute to the success of our organization.The salary for this role is estimated to be around £80,000 - £100,000 per...
-
Postdoctoral Research Scientist
1 month ago
York, York City, United Kingdom University of York Full timeRoleWe are seeking a highly motivated Postdoctoral Research Associate to join our team at the University of York. The successful candidate will have a PhD in Molecular Biology, Cell Biology or Microbiology and will be responsible for characterising the signalling pathways that regulate autophagy, lysosome exocytosis and biomolecular condensates during the...
-
York, York City, United Kingdom undisclosed Full timeAbout the RoleWe are looking for a skilled Research and Development Scientist to join our team at a leading Biotech company in York.The successful candidate will be responsible for supporting the development of lateral flow related projects, from feasibility through scale up into manufacturing.As part of the R&D team, you will oversee and plan the work of...
-
Scientific Research Associate
1 month ago
York, York City, United Kingdom York Bio Full timeJunior Bioanalytical Scientist (LCMS-Bioanalysis) - YorkWe are seeking a highly skilled and motivated Junior Bioanalytical Scientist to join our team at York Bioanalytical Solutions. As a leading provider of bioanalytical services to the pharmaceutical industry, we value our staff and provide a top-quality scientific service to our clients.The successful...
-
Clinical Biochemistry Specialist
2 weeks ago
York, York City, United Kingdom York and Scarborough Teaching Hospitals NHS Foundation Trust Full timeWe are seeking a highly skilled and experienced Clinical Scientist to join our dynamic team in Clinical Biochemistry at York and Scarborough Teaching Hospitals NHS Foundation Trust. The successful candidate will be responsible for providing clinical and scientific advice to healthcare professionals on the selection, performance, and interpretation of...
-
Senior Bioimage Analyst
4 weeks ago
York, York City, United Kingdom University of York Full timeAbout the RoleWe are seeking a highly skilled Research Scientist to join our team at the University of York, working on a Wellcome Trust-funded project to develop advanced bioimage analysis tools. The successful candidate will be responsible for driving their independent research project, managing complex imaging datasets, and collaborating with...
-
Machine Learning Innovator
3 weeks ago
York, York City, United Kingdom Hiscox Full timeAbout the RoleWe are seeking an experienced Machine Learning Engineer to join our newly formed data science team. This is an exciting opportunity to shape the data science delivery pipeline and contribute to the gradual transition of research models into production.Key ResponsibilitiesOwnership of the deployment framework for all data science services,...
-
Commercial Sales Representative
4 weeks ago
York, York City, United Kingdom A.U.G. Signals Ltd. Full timePosition: Business Development and Sales RepresentativeEducation: Bachelor's degree in relevant fieldKey Responsibilities:Proactively identify new sales opportunities across various customer segments through networking, prospecting, and cold callingQualify leads through cold-calling, cold-emailing, or LinkedIn outreach and arrange meetingsAnalyze opportunity...
-
BioPharma Workflow Solutions Architect Lead
4 days ago
York, York City, United Kingdom Lifelancer Full timeLife Sciences Innovations Group (LSIG) is a leading commercial team driving high-level collaborations and partnerships with BioPharma Strategic Partnership Accounts.The role of the BioPharma Workflow Solutions Architect is crucial in engaging technically with these workflows internally and deploying them to our partnership accounts. This position offers...
-
Machine Learning Engineer
4 weeks ago
York, York City, United Kingdom Hiscox Full timeAbout the RoleWe are seeking an experienced Machine Learning Engineer to join our newly formed data science team at Hiscox. As a key member of the team, you will have the opportunity to shape the data science delivery pipeline by building the infrastructure to acquire data from the data platform, deploy models, maintain, monitor, and upgrade core data...
-
Research Associate
6 months ago
University of York, United Kingdom University of York Full time**ESRC Vulnerability and Policing Futures Research Centre**: Are you an ambitious mixed methods researcher looking for your next challenge? Do you have a research interest in policing and vulnerable groups, and the interactions between them and other service providers? Are you committed to advancing and shaping policies and practice in policing futures? Do...
-
5 Year Independent Research Fellowship in
5 months ago
University of York, United Kingdom University of York Full timeWe are aiming to recruit a new group leader in human epithelial cancer, whose research expertise and interests can build upon existing strengths across the Department and University. We are looking for a scientist, potentially at an early stage of their independent career, with a strong, competitive track record and exciting ideas to develop an independent...
-
Assistant Scientist- Chemical Safety
5 months ago
York, United Kingdom FERA SCIENCE LTD Full time**Join us as an Assistant Scientist (Chemical Safety) and make an invaluable contribution to our Food Safety & Biosecurity!** At Fera, we’re making the world a better, healthier and safer place. We’re a joint venture partnership between Bridgepoint and Defra and we’re working proactively to protect the world we live in and the food we eat. Our teams...
-
Claims Data Scientist
6 months ago
York, United Kingdom Hiscox Full timeJob Type: Permanent Build a brilliant future with Hiscox Data Scientist – Group Claims Reporting to the Group Claims Data & Insights Manager London/York/Atlanta/Lisbon – Hybrid working The role: The Data Scientist is a technically excellent problem-solver responsible for providing in depth analysis across our diverse portfolio in...
-
Postdoctoral Research Associate
6 months ago
University of York, United Kingdom University of York Full time**Department**: We are also part of the York Biomedical Research Institute and of the Hull York Medical School. **Role**: The Fielding laboratory is seeking a post doctoral research associate to work on the cancer associated fibroblasts (CAF) in acute lymphoblastic leuakemia (ALL) for 3 years. We recently identified a key component of the niche that...
-
Assistant Laboratory Scientist
6 months ago
York, United Kingdom Animal and Plant Health Agency Full time**Details**: **Reference number**: - 309939**Salary**: - £22,150- Pro-rata salary for job share- A Civil Service Pension with an average employer contribution of 27%**Job grade**: - Administrative Officer**Contract type**: - Permanent**Type of role**: - Science**Working pattern**: - Full-time, Job share, Part-time**Number of jobs available**: -...
-
Machine Learning Engineer
6 months ago
York, United Kingdom Hiscox Full timeJob Type: Permanent Build a brilliant future with Hiscox Position: Machine Learning Engineer Reporting to: Lead Data Scientist Band: II Location: York - Hybrid Introduction We are looking for an experienced machine learning engineer to join a newly formed data science team. You will have the opportunity to...