Cell Expression Development Expert

3 days ago


Cambridge, Cambridgeshire, United Kingdom Lonza Group Ltd. Full time

R&D Lead Scientist Opportunity

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Lonza Cambridge is looking for a talented Cell Line Development Lead Scientist to join our team. As a key member of our R&D team, you will contribute to the delivery of new CHO-based mammalian expression hosts and vector systems for the expression of complex therapeutic proteins.

Key Responsibilities:

  1. Contribute to the delivery of new CHO-based mammalian expression hosts and vector systems for the expression of complex therapeutic proteins.
  2. Explore innovative ideas to optimise the cell line development (CLD) process including the use of state-of-the-art automation equipment, novel technologies, and more, to push the limits of what's possible.
  3. Independently lead several collections of projects from design and execution of experiments to data analysis and presenting of findings with confidence and clarity.
  4. Work closely with cross-functional groups within & outside of R&D to deliver solutions or improvements in recombinant protein expression and support commercialisation.

Requirements:

  1. PhD degree/Postdoctoral fellow with relevant experience in an R&D setting or BSc/Masters with relevant experience.
  2. Proven experience in mammalian cell line development and implementation/development of automation for cell line screening and optimisation, ideally within a high-stakes industrial environment.
  3. Proficiency in CHO cell culture, stable transfection, single cell isolation (i.e., Beacon Opto-fluidic Technology), clonal expansion, and small-scale bioreactors (i.e., Ambr15).
  4. Ability to translate basic scientific concepts into practical applications and integrate scientific knowledge to solve problems and issues. Communicate and apply scientific ideas effectively.

Estimated Salary Range: £65,000 - £85,000 per annum



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