Cell Expression Development Expert
3 days ago
R&D Lead Scientist Opportunity
">Lonza Cambridge is looking for a talented Cell Line Development Lead Scientist to join our team. As a key member of our R&D team, you will contribute to the delivery of new CHO-based mammalian expression hosts and vector systems for the expression of complex therapeutic proteins.
Key Responsibilities:
- Contribute to the delivery of new CHO-based mammalian expression hosts and vector systems for the expression of complex therapeutic proteins.
- Explore innovative ideas to optimise the cell line development (CLD) process including the use of state-of-the-art automation equipment, novel technologies, and more, to push the limits of what's possible.
- Independently lead several collections of projects from design and execution of experiments to data analysis and presenting of findings with confidence and clarity.
- Work closely with cross-functional groups within & outside of R&D to deliver solutions or improvements in recombinant protein expression and support commercialisation.
Requirements:
- PhD degree/Postdoctoral fellow with relevant experience in an R&D setting or BSc/Masters with relevant experience.
- Proven experience in mammalian cell line development and implementation/development of automation for cell line screening and optimisation, ideally within a high-stakes industrial environment.
- Proficiency in CHO cell culture, stable transfection, single cell isolation (i.e., Beacon Opto-fluidic Technology), clonal expansion, and small-scale bioreactors (i.e., Ambr15).
- Ability to translate basic scientific concepts into practical applications and integrate scientific knowledge to solve problems and issues. Communicate and apply scientific ideas effectively.
Estimated Salary Range: £65,000 - £85,000 per annum
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