Computational Biology Research Scientist

4 weeks ago

London, Greater London, United Kingdom Isomorphic Labs Limited Full time
Computational Biology Research Scientist

Isomorphic Labs Limited is a pioneering company that is reimagining drug discovery through a computational- and AI-first approach. We are seeking a highly skilled Computational Biology Research Scientist to contribute to our ambitious research programme, working in partnership with leading ML researchers, Chemists and Biological Scientists.

  • Partner with our Drug Discovery teams and wider organisation to use pioneering Computational Biology methods to drive data-enabled drug development.
  • Develop and apply Computational Biology workflows to address common drug development research questions, spanning from target identification to clinical biomarker strategies.
  • Use your expertise in computational biology datasets, spanning statistical genetics, genomics, transcriptomics, proteomics, functional perturbation screens, imaging, knowledge graphs, PPI, clinical and other data types, to devise relevant computational experiments.
  • Use data to drive biological insights and contribute to drug discovery programmes, becoming an integral member of project teams.
  • Work in partnership with the Computational Biology research team members to evaluate experimental models under development and benchmark to existing methodologies.
  • Work with Bioinformatics, Data and other groups to influence Iso's datasets and pipelines strategy, ensuring innovative insights are consistently brought to bear within drug development programmes.
  • Perform thorough data analysis and data quality assurance checks, with a strong focus on accuracy and reproducibility, inline with industry standard processes.

As a Computational Biology Research Scientist, you will have the opportunity to work on cutting-edge projects, collaborate with a talented team, and contribute to the development of innovative computational biology methods.

We are looking for a highly motivated and experienced researcher with a strong background in computational biology, a PhD, and/or extensive experience in the field. You should have expertise in detailed data quality control procedures and data visualisation, solid experience with experimental design and statistical analysis, and a solid understanding of computational biology tools and methodologies and experience with the analysis of large -omics datasets.

Additionally, you should have a demonstrated understanding of the principles of molecular cell biology and genetics, or related biological disciplines, familiarity with data processing pipelines and tools, and the ability to effectively communicate scientific concepts to a variety of audiences.

We offer a competitive salary and benefits package, as well as opportunities for career growth and professional development.

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