Senior Biologics Designer

3 days ago


Oxford, Oxfordshire, United Kingdom Immunocore Full time £75,000 - £90,000

We are seeking a highly skilled Senior Biologics Designer to join our team at Immunocore. As a world-leading biotech company, we are pioneering the development of transformative medicines that address unmet patient needs in oncology, infectious diseases, and autoimmune disease.

In this role, you will provide expert-level guidance on the design and optimisation of novel antibody and TCR drugs using advanced machine learning (ML) models. You will work closely with interdisciplinary teams across structural biology, next-generation sequencing (NGS), and bioinformatics and data science to integrate ML into TCR discovery and optimisation.

The successful candidate will have a strong publication record in antibody or biologics design, with at least 8 years of experience in the field. They will also have advanced Python programming skills, focusing on data science and machine learning, as well as expertise in structural biology and modelling.

Key responsibilities include:

  • Developing and assessing advanced ML models for novel antibody and TCR drug candidate optimisation
  • Utilising in-house structural and specificity data sets to extract further value
  • Working with colleagues across Research to identify training data from the public domain and help shape the development of in-house data sets
  • Driving the establishment of virtual screening tools, including TCR library design for multifactorial lead optimisation

We offer a competitive salary of $150,000 - $180,000 per annum, depending on experience.



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