Senior Biological Researcher

2 weeks ago


Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full time

The University of Cambridge invites applications for a Postdoctoral Research Associate position in human 3D organoid-based disease modelling. The successful candidate will explore the interactions between genomic changes and molecular pathways relevant to early pathologies and the progression of ALS using cutting-edge human CNS organoid models/tissue engineering and patient samples.

Key Responsibilities:

  • Design and execute experiments to investigate the relationships between genomic changes and molecular pathways in ALS.
  • Analyze data from human CNS organoid models and patient samples to identify potential therapeutic targets.
  • Collaborate with colleagues to develop and implement new experimental approaches.
  • Publish research findings in top-tier scientific journals.

Requirements:

  • PhD or MD in biological or medical sciences.
  • Practical experience with stem cell or cell-line cultures, general cell and molecular biology methods, vector preparation, and cloning.
  • Desirable skills: human stem cell- or organoid-based cultures, genetics and CRISPR-editing, single-cell transcriptomics, proteomics, or molecular pathology expertise.

Salary: £40,000 - £45,000 per annum (depending on experience). This is a fixed-term appointment for two years.

About the Role: This is an exciting opportunity to join a vibrant research team at the University of Cambridge, working at the intersection of basic biology and translational science. The successful candidate will have the opportunity to work with leading researchers in the field and contribute to the development of new treatments for ALS.



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