Senior Scientist, Crystallisation Expert
1 day ago
We are seeking a highly skilled Senior Scientist to join our Crystallisation team at Pharmaron. As a technical expert in Crystallisation, you will have the opportunity to work on a variety of analytical techniques, support materials science, analytical chemistry, formulation development, chemical engineering, and process chemistry projects.
Key Responsibilities:- Support crystallisation and isolation process development through laboratory experiments and materials characterisation assessment of starting materials, intermediates, and APIs.
- Monitor reaction pathways and kinetics using appropriate PAT.
- Conduct analysis of product samples for key physical properties, including XRPD, optical microscopy, PSD, and other relevant techniques.
- Assess polymorph landscape for final APIs and define thermodynamically stable form.
- Assess solubility in a variety of media using appropriate methods.
- Support clients in helping to define final salt and polymorphic form based on a full materials characterisation assessment.
- Support preformulation assessment of final phases.
- Work within project teams to tight deadlines.
- Able to step in and learn new techniques to support projects.
- Able to solve complex scientific problems.
- Able to work effectively in a GMP laboratory.
- Present and communicate clearly and effectively with clients.
- PhD in chemistry or relevant related subject with a technical focus on crystallisation for purity upgrade or particle engineering or PAT (additional industrial or academic experience preferred), or an MSC in chemistry with several years relevant industrial experience in crystallisation development or PAT.
- Knowledge of crystallisation methodologies relevant to drug substances.
- Familiarity with in-situ process analytical technologies for crystallisation process development (desired).
- Knowledge of data analytics and data visualisation tools.
- Knowledge of Design of Experiments (DoE) and related software (Desired).
- Significant expertise in troubleshooting and developing materials characterisation methods, including XRPD, DSC, TGA, DVS, Microscopy, and PSD. In-depth, hands-on expertise and up-to-date knowledge of other analytical methodologies.
- Experience using the following equipment would also be desired, although not essential: Technobis Crystal 16, Crystalline or Crystal breeder, Mettler React IR, FBRM, Easymax, other Spectroscopic PAT such as NIR or Raman.
- Strong scientific record of accomplishment.
We offer a competitive salary and a progressive and comprehensive suite of employee benefits. Our Hoddesdon campus in Hertfordshire is a hub of innovation and excellence, with over 5,000m2 of premier R&D space, including state-of-the-art GMP facilities for API, formulation, and process chemistry. We are looking for a Principal Scientist with strong expertise in Analytical Chemistry to join our growing team.
This is an opportunity for you as a Chemistry professional to make a real impact in a highly scientific and regulated environment, demonstrate leadership, ambition, and the desire to grow with the department. Build and shape your career in an environment that sets and commits to the highest standards of Chemistry. To be part of a team who support each other, embrace and solve technical challenges, and put excellence at the heart of all that we do.
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Senior Scientist, Crystallisation Expert
5 days ago
Hoddesdon, Hertfordshire, United Kingdom Pharmaron Full timeSenior Scientist, CrystallisationWe are seeking a highly skilled Senior Scientist to join our Crystallisation team at Pharmaron. As a technical expert in Crystallisation, you will have the opportunity to leverage your advanced knowledge in analytical techniques to support materials science, analytical chemistry, formulation development, chemical engineering,...
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Senior Scientist, Crystallisation Expert
5 days ago
Hoddesdon, Hertfordshire, United Kingdom Pharmaron Full timeSenior Scientist, CrystallisationWe are seeking a highly skilled Senior Scientist to join our Crystallisation team at Pharmaron. As a technical expert in Crystallisation, you will have the opportunity to leverage your advanced knowledge in analytical techniques to support materials science, analytical chemistry, formulation development, chemical engineering,...
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Hoddesdon, Hertfordshire, United Kingdom Pharmaron Full timeSenior Scientist, CrystallisationWe are seeking a highly skilled Senior Scientist to join our Crystallisation team at Pharmaron. As a technical expert in Crystallisation, you will have the opportunity to leverage your advanced knowledge in analytical techniques to support materials science, analytical chemistry, formulation development, chemical engineering,...
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