Separation and Purification Expert

4 weeks ago


Oxford, Oxfordshire, United Kingdom Exscientia Full time

About Exscientia

We are a pioneering AI-driven precision medicine company dedicated to discovering, designing, and developing innovative treatments for patients. Our cutting-edge platform enables us to guide treatment selection and improve patient outcomes in a prospective interventional clinical study.

The Role

We are seeking a highly skilled Separation and Purification Scientist to join our team at our state-of-the-art automated laboratory. As a key member of our synthetic chemistry team, you will develop and operate our analytical and purification tools, leveraging your expertise in compound analysis and purification to support our fully automated synthesis capability.

Key Responsibilities

  • Implement new technology to support automated analytical and purification / separation workflows.
  • Collaborate with ADME to support experimental physicochemical parameter measurement such as Chrom logD and EPSA.
  • Deliver rapid achiral and chiral purification processes for both automated and conventional synthesis workflows.
  • Support automated QC and quantitation workflows using LC-MS and Charged Aerosol Detection.
  • Collaborate with internal and external stakeholders to implement customised software or AI solutions for data manipulation and exploitation.

Requirements

Essential skills:

  • Minimum BSc qualification in Chemistry or Pharmaceutical Science, including at least 6 months industrial or academic working experience in Separation Science.
  • Proficiency in analytical LC-MS and / or SFC-MS with a basic understanding of chirality and isomer separation strategies within drug discovery. Proficiency in the operation of mass and / or UV guided purification systems.
  • Proven ability to apply separation science to solve complex problems, and ability to troubleshoot and maintain LC-MS instruments.
  • Innovation mindset with an open-minded attitude to drug discovery technologies and enthusiasm to challenge the status-quo.
  • Ability to work in high performing, cross functional teams with a collaborative mindset.
  • Strong written and verbal communication skills, as you will liaise with various teams and present your data to colleagues.

Benefits

Why Exscientia?

  • We offer a dynamic and inclusive work environment that fosters creativity and innovation.
  • Our team is passionate about making a difference in patients' lives through precision medicine.
  • We provide opportunities for professional growth and development, with access to cutting-edge technologies and expertise.
  • Our benefits package includes competitive salaries, annual bonuses, and share awards, as well as comprehensive private health insurance, dental and vision benefits, and a generous pension scheme.

DEIB

We are committed to building a diverse, equitable, and inclusive environment where every employee belongs. We celebrate and value the diversity of our team, recognising that our differences drive our creativity and innovation forward. If you require any support or adjustments to interact with us, please email us at [insert email address].



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