Separation and Purification Expert

4 weeks ago


Oxford, Oxfordshire, United Kingdom Exscientia Full time

About Exscientia

We are a pioneering AI-driven precision medicine company dedicated to revolutionizing the drug discovery process. Our cutting-edge platform enables us to design, develop, and deliver innovative treatments at an unprecedented pace.

The Role

We are seeking a highly skilled Separation and Purification Scientist to join our team at Exscientia. As a key member of our synthetic chemistry team, you will be responsible for developing and operating our analytical and purification tools. Your expertise in compound analysis and purification will be instrumental in supporting our fully automated synthesis capability.

Key Responsibilities

  • Implement new technologies to support automated analytical and purification workflows.
  • Collaborate with ADME to support experimental physicochemical parameter measurement.
  • Deliver rapid achiral and chiral purification processes for both automated and conventional synthesis workflows.
  • Support automated QC and quantitation workflows using LC-MS and Charged Aerosol Detection.
  • Collaborate with internal and external stakeholders to implement customised software or AI solutions for data manipulation and exploitation.

Requirements

Essential Skills

  • Minimum BSc qualification in Chemistry or Pharmaceutical Science, including at least 6 months industrial or academic working experience in Separation Science.
  • Proficiency in analytical LC-MS and / or SFC-MS with a basic understanding of chirality and isomer separation strategies within drug discovery.
  • Proven ability to apply separation science to solve complex problems, and ability to troubleshoot and maintain LC-MS instruments.
  • Innovation mindset with an open-minded attitude to drug discovery technologies and enthusiasm to challenge the status-quo.
  • Ability to work in high performing, cross functional teams with a collaborative mindset.

Desirable Skills

  • Experience with batch / plate analysis and automating data processing workflows for QC applications.
  • Experience with physicochemical parameter measurement using HPLC and SFC methodologies.

What We Offer

  • Competitive salary and bonus scheme.
  • Opportunity to work with a cutting-edge technology platform.
  • Collaborative and inclusive work environment.
  • Access to learning and development opportunities.
  • Generous holiday allowance and flexible working arrangements.

At Exscientia

We are committed to building a diverse, equitable, and inclusive environment where every employee belongs. We celebrate and value the diversity of our team, recognising that our differences drive our creativity and innovation forward.



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