Immunology Specialist

6 days ago

Cambridge, Cambridgeshire, United Kingdom UK Research and Innovation Full time
Job Description

Overall Purpose:

To work within the group of Dr. Patrycja Kozik at the MRC Laboratory of Molecular Biology (LMB), within a programme aimed at investigating initiation immune responses by dendritic cells.

Main Duties:

  • To undertake research aimed at characterising molecular mechanisms involved in dendritic cell functions.
  • To identify, develop and apply a broad range of techniques to pursue the research objectives.
  • To present scientific work at seminars within the laboratory and at external meetings.
  • To contribute to laboratory-wide discussions on developments within the field.
  • To draft scientific papers, and contribute to the overall preparation of research for publication.
  • To contribute to the LMB's mission in the public engagement of science, and the translation of research findings into improvements in health care.
  • To assist in the training of PhD students and other members of the LMB.

Key Responsibilities:

  • Within the overall direction of the programme, the group, the remit of the project and in discussion with the Group Leader, you will make a significant input into determining the direction of the project within a three year lifespan.
  • To plan your own work and objectives on a 12-month basis and manage your experimental work within the project along with your Supervisor.
  • To work with limited supervision to identify, develop, modify and apply the necessary techniques to achieve the goals of the project.
  • To introduce and apply new techniques across a wide range of disciplines and to have the creativity and initiative to develop novel approaches and methods where required.
  • To ensure the research is carried out in accordance with good practice and in compliance with local policies and legal requirements.
  • To contribute to the smooth running of the group, including the effective use of resources, training of others and taking responsibility for use of communal facilities.
  • To enhance your research and generic skills through a tailored development programme.

Working Relationships:

You will report to Dr. Patrycja Kozik and will interact and collaborate with other Postdoctoral Scientists, Research Support staff and students, not only in your group, but also across the LMB and with external groups as necessary.

Additional Information:

This is a three-year training and development position for a Postdoctoral Scientist who has recently completed their doctoral studies, is moving into a new research discipline or has limited experience of key transferable skills.

We support Postdoctoral Scientists with a range of formal and on-the-job training, including:

  • MRC training courses.
  • External training and personal development courses.
  • One-to-one training with your Supervisor and other Scientists.

You will commit to undertaking the following:

  • Developing and following a personal development plan.
  • Attending training courses.
  • Identifying additional training which will support you to develop your career.

Person Specification:

Academic Qualifications:

These should include a PhD in molecular biology, cell biology, or immunology or due to complete PhD within 6 months.

Technical Skills and Expertise:

Solid knowledge of dendritic cell biology.

Experience of and ability to perform techniques relevant to the project. Particularly useful would be:

  • Experience with assays to study antigen trafficking, processing and presentation.
  • Experience with assays to study MHC class I biology.
  • Experience with relevant mouse models to study DC role during immune responses against pathogens and tumours as well as during inflammatory diseases.
  • Experience with multi-colour flow cytometry including extracellular and intracellular staining.
  • Experience of isolation and preparation of primary cells.

Track Record of Research:

This will include achievements, and contributions to published papers.

Other Relevant Evidence of:

Commitment.

Originality.

Ability to communicate.

Working with others.

Additional Information:

The position would suit an individual who enjoys working in a collaborative environment, manages their time effectively and is motivated by addressing challenging research questions.

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