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Computational Chemistry Specialist
2 months ago
CK Group is collaborating with a leading biopharmaceutical organization to recruit two Computational Chemistry Specialists to enhance their Computational Chemistry division.
We invite applications from individuals who have recently earned a PhD in computational chemistry, cheminformatics, or a related field, as well as those with several years of postdoctoral experience.
This biopharma company is dedicated to developing innovative specialty medicines aimed at improving the quality of life for patients facing unmet medical needs worldwide.
Their research pipeline is concentrated on addressing significant unmet medical requirements in rapidly evolving therapeutic areas, including CNS, GI, immunology, metabolic disorders, and rare diseases. They utilize their proprietary and industry-leading GPCR-targeted structure-based drug discovery platform to ensure a consistent supply of best- or first-in-class candidates.
The organization has established exceptional capabilities in their platform, discovery, and translational medicine teams, facilitating the advancement of multiple programs from preclinical stages to early clinical development.
There are remarkable opportunities for Computational Chemistry Specialists to expand their expertise in Computer-Aided Drug Design and Cheminformatics/AI within this organization.
This role is particularly exciting as it involves leveraging the advanced platform to support structure-based computational design in drug discovery initiatives and to develop innovative methodologies and workflows for broader applications.
Key Responsibilities:
- Collaborate with essential stakeholders across various disciplines to define and implement computational strategies that support project delivery across the portfolio.
- Utilize a comprehensive array of computational and cheminformatics tools, workflows, and models to extract, integrate, analyze, and visualize complex chemical, structural, pharmacological, and ADMET data to facilitate novel molecule designs.
- Identify and assist in the development of innovative computational tools that enhance the drug design process, including:
- Structural bioinformatics and platform technology approaches
- Creation of new computational chemistry CADD software through external partnerships
- Development and implementation of tailored computational tools for internal research and development
Qualifications:
- PhD or equivalent experience in computational chemistry, cheminformatics, or a related discipline.
- Experience in CADD within a collaborative, multidisciplinary medicinal chemistry research environment.
- Proficient knowledge and hands-on experience with molecular modeling, computer-aided drug design, and cheminformatics software packages.
- Demonstrated independent initiative, advanced analytical and critical problem-solving skills, along with scientific innovation and integrity.
- Experience in employing CADD techniques for hit identification and exploring protein-ligand interactions using data-driven and physics-based methodologies, preferably in the pharmaceutical or biotech sectors.
- Background in drug discovery related to protein design and/or membrane proteins.
- Programming and scripting skills (e.g., Python) or familiarity with pipelining tools.
- Additional experience in cheminformatics or bioinformatics is advantageous.
Benefits:
- State-of-the-art research and development center.
- Competitive compensation package, including discretionary cash bonuses.
- Eligibility for grants of Restricted Stock Units.
- 25 days of annual leave plus public holidays, with the option to purchase an additional 5 days each year.
- Employer contributions to pension plans.
- Private Medical Insurance for employees and their families, along with a cash plan for dental and optical reimbursements.
- Health and wellness benefits, including a subsidized gym membership.
- Income protection for long-term health-related absences.
