Bioinformatics Research Scientist
4 weeks ago
Position Overview
The Rakyan laboratory is dedicated to exploring the genetic and epigenetic factors that govern mammalian Ribosomal DNA (rDNA). Utilizing advanced molecular biology techniques alongside sophisticated computational methodologies, we aim to uncover the genetic and epigenetic dynamics that play a crucial role in rDNA biology. Our hypothesis posits that genetic diversity within rDNA can significantly influence both molecular and phenotypic expressions. To validate this, we are engaged in extensive integrative analyses of human whole-genome sequencing datasets. Our focus includes leveraging both short- and long-read sequencing data to investigate the relationships between genetic variation in human rDNA and the onset of diseases, such as cancer, while also tracing the evolutionary lineage of rDNA variations.
Candidate Profile
The ideal applicant will possess a PhD in a relevant discipline, such as computational biology or bioinformatics, complemented by several years of postdoctoral experience in analyzing repetitive genomic regions. Proficiency in programming languages such as R, Python, Java, Matlab, C, and MySQL is essential. Experience in Genome-Wide Association Studies (GWAS), whole genome sequencing analysis, and computational analyses of epigenomic and transcriptomic data is required. Candidates must demonstrate their expertise through a portfolio of first-author publications in pertinent fields. Additionally, the successful candidate will be expected to mentor junior lab members and contribute to grant proposal writing.
About the Institute
Established in 2003, the Blizard Institute is one of six institutes within the Faculty of Medicine and Dentistry at Queen Mary University of London. With a dedicated team of approximately 350 staff members across four academic centers and one Public Engagement Center, the Institute supports around 750 postgraduate research and taught students. Our mission is to excel in research, education, and clinical services.
About Queen Mary University
At Queen Mary University of London, we champion the idea that diverse perspectives foster groundbreaking achievements. Our history reflects a commitment to social justice and enhancing lives through academic excellence. We strive to maintain this ethos today, not merely as a moral obligation but as a catalyst for intellectual innovation.
We actively promote a culture of diverse thought and dialogue, believing that the intersection of varying viewpoints and disciplines leads to the emergence of truly original ideas.
Benefits
We offer competitive remuneration, access to a robust pension scheme, and 30 days of annual leave (pro-rata for part-time or fixed-term roles). Additional benefits include a season ticket loan scheme and a wide array of personal and professional development opportunities. We also prioritize work-life balance and family-friendly policies, offering flexible working arrangements.
Queen Mary University is committed to fostering a diverse and inclusive community, which is reflected in our recruitment processes. We will make reasonable adjustments throughout the recruitment process for candidates with disabilities and are open to considering flexible working arrangements.
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Bioinformatics Research Scientist
4 weeks ago
Canary Wharf, Greater London, United Kingdom Queen Mary University of London Full timePosition Overview The Rakyan laboratory is dedicated to exploring the genetic and epigenetic factors that govern mammalian Ribosomal DNA (rDNA). Utilizing advanced molecular biology techniques alongside sophisticated computational methodologies, our aim is to unravel the genetic and epigenetic intricacies that play a role in various aspects of rDNA...
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