Post-doctoral Fellow

3 weeks ago

University, United Kingdom Springer Nature Full time

**Post-Doctoral Fellow**:

- Employer- University of Colorado-David Schwartz Lab- Location- University of Colorado Medical Center, Denver- Salary- $56,484 to $70,000- Closing date- 8 Apr 2024- Discipline
Applied Science
Job Type
Postdoctoral
Employment - Hours
Full time
Duration
Permanent
Qualification
PhD
Sector
Academia- You need to sign in or create an account to a job.

Post-Doctoral Fellow - 32918 Faculty Description **University of Colorado Anschutz Medical Campus**

**Department: Medicine/Pulmonary Sciences and Critical Care**

**Job Title: Post-Doctoral Fellow**

**Position #:00820700 - Requisition #:32918**

**Job Summary**:
In the laboratory, we use genome editing approaches to manipulate genetic variants and expression of key genes in primary cell and animal models. Computational approaches include genetic screens for genes that interact with _MUC5B_, identification of biomarkers of early disease, and single cell and spatial transcriptomic technologies. Our ultimate goal is to understand the early mechanisms of lung fibrosis, develop biomarkers for early detection, and ultimately identify therapeutics for early treatment of disease.

We are looking for individuals interested in developing skills in various aspects of functional genomics.

Key Responsibilities:

- Mechanism regulating lung injury and early lung fibrosis with an emphasis on MUC5B, ER stress, apoptosis, cilia function and mucus clearance, and biophysical dysfunction of distal airway epithelia Characterization of novel animal model of Muc5b-driven lung fibrosis Role of lncRNAs in modifying the genetic susceptibility in pulmonary fibrosis Understand how the gain-of-function MUC5B promoter variant affects transcriptional regulation and gene expression in distinct types of MUC5B-driven usual interstitial pneumonia (using snRNAseq, snATACseq, and spatial transcriptomics) Early diagnostic and prognostic biomarkers of interstitial lung disease Determine the genetic variants in IPF among non-European populations

**Work Location**:
**On Site** -onsite location is at the Anschutz Medical Campus in Aurora, Colorado and schedule will be coordinated with supervisor.

**Why Join Us**:
About the Division of Pulmonary Sciences and Critical Care Medicine

Thank you for your interest in the Division of Pulmonary Sciences and Critical Care Medicine at the University of Colorado Our over 140 faculty are located across four sites: the University of Colorado Anschutz Medical Campus, National Jewish Health, Denver Health, and the VA Eastern Colorado Health Care System.

We are very proud of our long and illustrious history. Many seminal discoveries in pulmonary and critical care medicine occurred here in Denver, including advances in tuberculosis, interstitial lung disease, airway disease, cancer, and critical care. Many of our former trainees have taken leadership roles in academic medicine, including Division and Department Chairs, Deans, and American Thoracic Society Presidents.

We continue to enhance all aspects of our division and training program, and as a result, we have seen tremendous and sustained growth. The clinical practice sites have built new hospitals, and there are multiple new research buildings across the campuses. We have been fortunate to recruit tremendous new faculty members while retaining many of our former trainees.

About the University of Colorado Anschutz Medical Campus

Why work for the University?

We have AMAZING Benefits and offer exceptional amounts of holiday, vacation, and sick leave

The University of Colorado offers an excellent benefits package including:

- **Medical**: Multiple plan options
- **Dental**: Multiple plan options
- **Additional Insurance**: Disability, Life, Vision
- **Retirement 401(a) Plan**: Employer contributes 10% of your gross pay
- **Paid Time Off**: Accruals over the year
- Vacation Days: 22 (maximum accrual 352 hours)
- Sick Days: 15 (unlimited maximum accrual)
- Holiday Days: 10
- **Tuition Benefit**: Employees have access to this the benefit on all CU campuses
- **ECO Pass**: RTD Bus and light rail service

**Diversity and Equity**:
**Qualifications**:
**Minimum Qualifications**:

- Applicants must meet minimum qualifications at the time of hire._
- PhD, MD, or PhD/MD, preferably in pulmonary sciences

**Preferred Qualifications**:

- Previous experience in genetics, genomics, or epigenetics

**Knowledge, Skills, and Abilities**:

- Excellent oral and written communication skills Ability to work independently within the research laboratory

For full consideration, please submit the following document(s):
1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position

2. Curriculum vitae / Resume

**Screening of Applications Begins**:
**Anticipated Pay Range**:
The starting salary range (_or hiring range_) for this position has been established as **HIRING RANGE**:
**$56,484 to $70,000**

The above salary ran

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