Research Fellow

6 months ago

Plymouth, United Kingdom Plymouth University Full time

We are seeking a Research Fellow to work on the Small Business Research Initiative (SBRI) awarded program for the Tolerability and acceptability of subcutaneous EEG monitoring in people with epilepsy and intellectual disability based at the University of Plymouth.

Based in the Faculty of Health, the Peninsula Medical School aims to attract highly motivated and talented students to become the next generation of future-ready doctors, physician associates and radiographers, who are well prepared for a 21st Century career. The School’s innovative approach to education is underpinned by research and staff who are committed to scholarship that includes undertaking curriculum development and design activities.

The School takes pride in supporting the needs of the local region and recognises that providing excellent educational and personal development experiences, as well as world class research, requires true partnerships with key stakeholders from across the region and beyond. Our research - underpinned by significant grant capture - is translational, generates impact and serves our Peninsula population as well as having global impact.

A key strength is a close relationship with NHS partners, with early clinical contact for all students. The South West offers healthcare and learning opportunities of exceptional quality; University Hospitals Plymouth NHS Trust at Derriford is one of Europe’s largest hospitals and the only trauma centre in Devon and Cornwall.

Clinical research pathways within the School provide a research culture and environment that values talent and supports endeavour and innovation.

The School is strongly committed to equality, diversity and inclusion and holds an Athena Swan Silver Award recognising commitment to maintaining a culture of participation and inclusivity across all activities. The School is also signed up to the BMA Racial Harassment Charter which offers guidance and best practice to address the unacceptable barriers faced by BAME students as they negotiate their different learning environments.

We are looking to appoint a Research Fellow who will work 100% on this research role for 12 months and have regular contact with, and support of, the Co-Investigator Professor Rohit Shankar, University of Plymouth.

Many people with intellectual disabilities (PwID) and autism have seizures. Electroencephalography (EEG), which measures the brain's electrical activity, is a crucial method of diagnosing and assessing seizures. This is generally conducted in a hospital, meaning patients can only be observed for a limited time and hospital stays can also be challenging and uncomfortable for PwID and autism.

UNEEG Medical has developed a very small device ('SubQ'), that can be put under the skin on a person's head to track their brain activity without staying in the hospital. It has been medically validated, CE-marked and successfully implanted for up to 15 months in people with seizures, but not in PwID and autism.

This project will build on co-production work conducted with people with PwID and autism, their family members, and their carers, to understand how this technology could be used to improve our understanding of epilepsy and seizures for PwID and autism, which patients it might be helpful for, and how to explain the technology to enable its uptake and use. This project aims to use our learnings from our Phase 1 project's co-production work to test the device's tolerability, acceptability and planned implementation in this population and gather initial evidence of how well it can detect seizures in people with moderate to profound ID and autism. We will also examine how it impacts patients' quality of life, behaviour, and carer experiences. Having an accurate means of identifying seizures is particularly important for people with moderate to profound ID, because they cannot tell us about their experiences.

This means seizures are more likely to be missed or attributed to behavioural issues.

Healthcare professionals at the Cornwall Partnership NHS Foundation Trust will identify 5 to 10 patients for whom the technology could provide clinical benefit. These patients will be invited to participate; as they lack the capacity to provide informed consent; their legal representative will make the decision based on their best interests. Patients who participate in the study will have the device implanted under the skin on their scalp. The patient's clinician will make decisions about when to remove the implant. Study data will be collected from the device six months after implantation, and questionnaire data will be collected from carers before implantation as well as immediately, three months, and six months after. We will invite some carers to discuss their experiences with the technology in more detail in an interview.

Carers of people with epilepsy and moderate to profound ID and autism will be invited to join the research group. They will be involved in planning and making de

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