Research Associate in Enzyme Design and Engineering

6 months ago


Manchester, United Kingdom The University of Manchester Full time

**Design and Engineering of Proteins with an Expanded Amino Acid Alphabet**

Positions are available for three Postdoctoral Research Associates with experience in directed evolution, biocatalysis, biochemistry or a related discipline. The aim of the research is to develop new functional proteins built from an expanded set of amino acids and methods for their production. This position is based in the Manchester Institute of Biotechnology (MIB) under the ssupervision of Prof Anthony Green and Dr Sarah Lovelock.

Nature uses twenty canonical amino acids to produce proteins with diverse structures and functions. However, these amino acids contain limited chemical diversity, restricting our ability to engineer proteins with new functions and desirable properties. In this project we develop efficient methods for selectively introducing non-canonical amino acids with new functional side chains into proteins. These methods will be optimized to allow economical production of proteins built using an expanded genetic code. We will subsequently capitalize on these new functional amino acids to develop enzymes in proteins with new functions.

The University will actively foster a culture of inclusion and diversity and will seek to achieve true equality of opportunity for all members of its community.

What you will get in return:

- Fantastic market leading Pension scheme
- Excellent employee health and wellbeing services including an Employee Assistance Programme
- Exceptional starting annual leave entitlement, plus bank holidays
- Additional paid closure over the Christmas period
- Local and national discounts at a range of major retailers

As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.

Our University is positive about flexible working you can find out more here

Hybrid working arrangements may be considered.

Any CVs submitted by a recruitment agency will be considered a gift.

**Enquiries about the vacancy, shortlisting and interviews**:
Name: Anthony Green or Sarah Lovelock

**General enquiries**:
**Technical support**:
**Please see the link below for the Further Particulars document which contains the person specification criteria.



  • Manchester, United Kingdom The University of Manchester Full time

    Applications are welcomed for this 36 month post based in the Manchester Institute of Biotechnology (MIB) and Department of Chemistry at The University of Manchester. The post aims to map QMT contributions to enzyme reactions along artificial enzyme evolutionary trajectories. This approach will involve the development and use of laboratory DE strategies,...


  • Manchester, United Kingdom CV-Library Full time

    What you will do Design, develop, and maintain production-ready software tools and frameworks for efficient enzyme design and analysis. Work closely with research scientists to transform innovative algorithms and generative models into robust, scalable software solutions. Implement and maintain data pipelines for processing and analysing large-scale...


  • Manchester, United Kingdom GCS Ltd Full time

    What you will do Design, develop, and maintain production-ready software tools and frameworks for efficient enzyme design and analysis. Work closely with research scientists to transform innovative algorithms and generative models into robust, scalable software solutions. Implement and maintain data pipelines for processing and analysing large-scale...


  • Manchester, United Kingdom The University of Manchester Full time

    We are seeking a highly skilled and ambitious postdoctoral researcher to join our team at The University of Manchester as a Lecturer in Chemical Biology. This is an excellent opportunity for a talented early career scientist to develop their research skills, build their expertise, and contribute to the advancement of chemical biology.Job DescriptionThe...


  • Manchester, United Kingdom The University of Manchester Full time

    Applications are invited for a Research Associate in Pharmacokinetic Translation and PBPK modelling, in the Division of Pharmacy and Optometry. The post will be tenable on a fixed term basis of 24 months in the first instance. Working under the umbrella of the Centre of Applied Pharmacokinetic Research (CAPKR) group, you will be fully involved in a...


  • Manchester, United Kingdom The University of Manchester Full time

    A 12-month 0.5 FTE postdoctoral research associate position is available with Dr Kristina Brubacher in the Department of Materials for an ambitious and talented researcher in the interdisciplinary field of apparel development, technology and engineering in the Apparel Design Engineering (ADE) research group at the University of Manchester. **What you will...


  • Manchester, United Kingdom CV-Library Full time

    PhD Research Scientist - Biotechnology required on a permanent basis in Manchester. Requiring a PhD in Biology, Biotechnology, Biochemistry (or similar), with an understanding of cell cultivation for producing metabolites, and knowledge of metabolic pathways and enzymes. An interest in personal care products and markets is desirable. Knowledge and/or...


  • Manchester, United Kingdom The University of Manchester Full time

    A Research Associate position is available for an outstanding and ambitious biomedical engineer to undertake research in the field of bioengineering research. In particular the researcher will be an important addition to Professor Cartmell’s research group by assisting with the leadership of Professor Cartmell’s research group and furthering research in...


  • Manchester, United Kingdom CV-Library Full time

    Our client is an award-winning MEP, Sustainability and Environmental Engineering and Design consultancy with teams of engineers, designers and technical specialists working across various sectors. Position: Associate Mechanical Design Engineer Location: Manchester Salary: - £negotiable depending on experience Working in partnership with our client,...


  • Manchester, United Kingdom The University of Manchester Full time

    We are seeking an outstanding and ambitious early career scientist to support the research of Prof Anthony Green as a Lecturer in Chemical Biology at The University of Manchester.The successful candidate will be expected to contribute enthusiastically to teaching and management, while carrying out research independently and in collaboration with Prof. Green....


  • Manchester, United Kingdom The University of Manchester Full time

    Background This is a new project taken in the smart manufacturing group led by Prof. Charlie Wang. The project aims to enable a deformable mannequin to facilitate the customised garment production for different body shapes by employing the many more degree-of-freeform deformation that can be provided by a soft robotic system rather than conventional...


  • Manchester, United Kingdom Centre People Appointments Ltd Full time

    **Biomedical Research Associate** A fast-growing biotech start-up is looking for a Biomedical Research Associate to join their research team in London and Manchester. The company’s focus is on technological development of reproductive cells with iPS and ES cells. This is an amazing opportunity for those looking to join the commercial industry from...


  • Manchester, United Kingdom The University of Manchester Full time

    We are seeking an ambitious and talented scientist to join our research team as an Academic Researcher in Chemical Biology. The successful candidate will support the research of Prof. Anthony Green, contributing to teaching, management, and carrying out research independently and in collaboration with Prof. Green.Key Responsibilities:Conduct innovative...


  • Manchester, United Kingdom Health Research Authority Full time

    As a key member of the HRA Digital team, you will lead the user research community in the development of digital services that prioritize user needs.The Digital Directorate is transforming the business, ensuring the user is at the heart of everything, including the delivery of business solutions using agile methods in a continuous delivery environment.You...


  • Manchester, United Kingdom The University of Manchester Full time

    This 1-year research associate post is based in the Power and Energy Division within the Department of Electrical and Electronic Engineering. The Power and Energy Division specialises in high voltage technologies, energy networks, power conversion/electrical drives and power electronics and is the largest UK academic group in this area with a long-standing...


  • Manchester, United Kingdom The University of Manchester Full time

    A Research Associate position is available at the University of Manchester to work on the UKRI/EPSRC funded project _ad-ASSTRA: Towards A Sustainable Space Technology Roadmapping Architecture_ (6-months) and the University of Manchester funded project Visions of, and steps towards, an Environmentally Sustainable Space Future (6-months). You will be working...


  • Manchester, United Kingdom Coop Full time

    **Associate User Researcher** Up to £30,500 plus great benefits (Work Level 6B) Manchester city centre (hybrid working) We’re looking for an Associate User Researcher to join our Digital Products & Design team in Manchester to collect insights that’ll help us to shape the online experience for our Funeralcare customers. In this role you’ll work in a...

  • Research Associate

    7 months ago


    Manchester, United Kingdom Manchester Metropolitan University Full time

    We have an exciting opportunity for a fixed term research associate to work full time on an Innovate UK-funded project. The project aims to develop advanced data analytics an d tools that empower female athletes with personalised insights and tailored training programs, that recognize the impact of the menstrual cycle on their athletic journey. This will...

  • Research Associate

    5 months ago


    Manchester, United Kingdom Digby Morgan Full time

    summary - _ manchester, north west_ - _ £28,000 - £40,000 per year_ - _ permanent_- specialism - sales- reference number - PR-1152579:MAN:A - job details Job Title: Research Associate **Salary**: £28,000 ( £12k OTE) Empowering finance professionals to work smarter, our client provides world-class solutions to finance teams and executives across the...


  • Manchester, United Kingdom Health Research Authority Full time

    Senior User Researcher Role OverviewThe Health Research Authority seeks a Senior User Researcher to lead user experience research projects and contribute to the development of digital services for customers. The post holder will manage a user research team, undertake user research activities, and provide training and mentorship for user researchers.Key...