Research Scientist

4 weeks ago


Cambridge Cambridgeshire, United Kingdom EC Resourcing Full time

Our client, a biopharmaceutical company based near Cambridge, is looking for a Scientist (T-Cell Engineering) to join their growing research team.
Planning and execution of a wide range of robust experiments, technical studies, and tasks, working independently based on protocols and in line with departmental objectives.
Inform and implement the design of novel genetic constructs for use in T Cell engineering .
Development of robust T Cell engineering platform.
Timely, accurate recording and analysis of results and compliance with data integrity procedures.
Timely presentation of data to the department and wider company.
Contribution to critical interpretation of data to draw results driven hypotheses, with influence on project/function direction.
A PhD with experience in T Cell biology (or equivalent experience gained in industry). Engineering of T Cells for the purpose of CAR-T generation with Lentiviral or CRISPR based systems is a plus.
Experience with CRISPR based editing of primary human T Cells, both KO and KI
Experience with genetic approaches for quantifying T Cell engineering outcomes.
Experience with assays of T Cell functionality and potency, especially in the context of CAR-T.
Fluency in spoken and written English.
Proficiency with critical interpretation of data and implementation into an experimental cascade.
Contribution to authoring of technical and science reports which will feed into IND filings.
Awareness of latest scientific literature in company-relevant projects and general scientific areas.


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