Assay & Cell Culture Scientist

2 months ago

Stevenage, Hertfordshire, United Kingdom PerkinElmer Full time

Job Responsibilities

Grow and maintain primary, mammalian and specialised cell lines (suspension, adherent, 3D organoids) to be used in biological assay work. Maintain cell biobank of patient derived organoids. Prepare conditioned media for successful maintenance of cells. Working with complex in vitro models (organoids, co-cultures and organ-on-chip systems) Cell fixing, staining and imaging Assay Work including MSD, ELISA, Immunohistochemistry, DNA/RNA extraction and more Ensure aseptic technique is adhered to in the maintenance of cells Adherence to Health and Safety procedures for own well-being and quality of product. Actively seek opportunities to develop the service by discussion with customer or by the sharing of best practice with other groups. Assist with the preparation of SOPs, Risk Assessments and best practice guides. Act as an ambassador for the Technical Laboratory Services Group and promote PerkinElmer's core values. Operate to approved quality standards. Work independently and flexibly depending on team priorities and set realistic work schedules to support requirements. Perform any other reasonable duties as requested by the line manager or project team leader. Preferred Education/Experience/Qualifications BSc or equivalent in relevant scientific subject (e.g. biology, biotechnology or Biomedical Sciences), with relevant laboratory experience. 1 year of demonstrated technical expertise/or equivalent in cell culture, general lab instrumentation, cell-based assays, immunoassays such as ELISA – This can be through an academic experience or workplacement Demonstrateable knowledge or understanding of cell culture, cell lines and aseptic technique. Understanding of standard software packages (i.e.: Microsoft Office) Highly motivated and independent, yet able to work well in a group setting. Ability to work independently and deliver high-quality, consistent results in a timely fashion. Ability to meet timelines successfully with the utmost attention to detail while setting high performance standards. Ability to understand, interpret, and communicate scientific data. Ability to execute new and established methods and protocols. Outstanding communication and interpersonal skills Physical Demands The overall physical exertion of this position requires: Sit or stand 4-5 hours in laboratory areas. Work around moving laboratory equipment and machinery. Work with biohazards such as blood borne pathogens. Hepatitis B vaccination will be required, Vaccination programme in place for successful candidates who are not already vaccinated or require updated boosters. All work is carried out in a containment level 2 environment. Appropriate PPE must always be worn (Lab coat, gloves, eye protection). Reach above/below the shoulder, bend at the knees and waist. Office work activities, including keyboard, up to 2-3 hours. Working Environment Must be able to work in a laboratory, controlled environments requiring personal protective equipment. Job pace may be fast and job completion demands may be high. Employee maybe required to manage hazardous wastes in compliance with company procedures & State/Federal/Local hazardous waste regulations. Duties may include: Identifying, handling, generating, accumulating, storing, labelling. Ensure safety, security, and the environment in all aspect of the daily activities, and any potential safety hazards are addressed and corrected immediately. Understand ergonomic relationship between people, equipment and working environment.

  • Lead Scientist in Molecular Biology and Laboratory Operations

    3 weeks ago

    Stevenage, Hertfordshire, United Kingdom Serna Bio Full time

    About Serna BioSerna Bio is pioneering the creation of the world's first comprehensive map of the druggable transcriptome, systematically unlocking the potential of RNA biology for small molecule drug discovery. Our innovative Discovery Platform is designed to address traditionally challenging targets, including both coding and non-coding RNA.Role OverviewWe...

  • Lead Scientist in Molecular Biology and Laboratory Operations

    3 weeks ago

    Stevenage, Hertfordshire, United Kingdom Serna Bio Full time

    About Serna BioSerna Bio is pioneering the first comprehensive map of the druggable transcriptome, systematically unlocking the potential of RNA biology for small molecule drug discovery. Our innovative Discovery Platform addresses traditionally challenging targets, including both coding and non-coding RNA.Position OverviewWe are seeking a dynamic Lead...

  • Lead Research Scientist

    3 weeks ago

    Stevenage, Hertfordshire, United Kingdom GlaxoSmithKline Full time

    Position Overview:We are in search of a dedicated and innovative scientist to join our team, focusing on the development of sophisticated in vitro models.Role Responsibilities:Design and implement advanced cellular systems that integrate immune system components.Conduct cell-based assays combined with imaging techniques to analyze organoids and...

  • Lead Scientist in Molecular Biology and Laboratory Operations

    3 weeks ago

    Stevenage, Hertfordshire, United Kingdom Serna Bio Full time

    About Serna BioSerna Bio is pioneering the development of the first comprehensive map of the druggable transcriptome, unlocking the potential of RNA biology for small molecule drug discovery. Our innovative Discovery Platform addresses traditionally challenging targets, including both coding and non-coding RNA.Role OverviewWe are seeking a dynamic Lead...

  • Principal Scientist

    3 weeks ago

    Stevenage, Hertfordshire, United Kingdom GlaxoSmithKline Full time

    Position Overview:We are looking for a dedicated and innovative bench scientist to join our team focused on the development of Complex In Vitro Models. This role is integral to our mission of enhancing the predictive and translational capabilities of preclinical models.Key Responsibilities:Design and implement sophisticated cellular models that integrate...

  • Advanced Scientist in In Vitro Technologies

    3 weeks ago

    Stevenage, Hertfordshire, United Kingdom GlaxoSmithKline Full time

    Position Overview:We are looking for a dedicated and innovative scientist to join our team, focusing on the development of sophisticated in vitro models. The ideal candidate will contribute to our mission of enhancing the predictive and translational capabilities of preclinical research.Key Responsibilities:Design and implement advanced cellular models that...

  • Lead Molecular Biology Scientist

    3 weeks ago

    Stevenage, Hertfordshire, United Kingdom Serna Bio Full time

    At Serna Bio, we are pioneering the creation of the first comprehensive map of the druggable transcriptome, unlocking the potential of RNA biology for small molecule drug discovery. Our innovative Discovery Platform is designed to address traditionally challenging targets, including both coding and non-coding RNA.Join Our TeamAs a member of our R&D team...

  • Biopharmaceutical Cell Line Development Senior Scientist

    3 months ago

    Stevenage, Hertfordshire, United Kingdom GlaxoSmithKline Full time

    Site Name: UK - Hertfordshire - StevenagePosted Date: Mar Biopharmaceutical Cell Line Development Senior ScientistThe Biopharm Cell Line Development (CLD) group is seeking to expand its team of enthusiastic and passionate scientists, dedicated to driving the progression of GSK's Biopharmaceutical portfolio by the delivery of high-quality cell lines,...

  • Senior Scientist

    3 weeks ago

    Stevenage, Hertfordshire, United Kingdom GlaxoSmithKline Full time

    Position Overview:We are looking for a dedicated and innovative scientist to join our team focused on developing Complex In Vitro Models. This role is crucial in enhancing the predictive and translational capabilities of preclinical models.Key Responsibilities:Design and implement sophisticated cellular models that integrate immune system components.Conduct...

  • Functional Genomic Automation Scientist

    2 months ago

    Stevenage, Hertfordshire, United Kingdom PerkinElmer Full time

    Job Purpose:The successful candidate with join the Perkin Elmer team working with Customer's Target Discovery to provide first line technical support for automated liquid handling and bench-top automation platforms, enabling minimal equipment downtime and maximal system utilization. This position will be embedded within the department, providing direct...

  • Advanced Research Scientist

    3 weeks ago

    Stevenage, Hertfordshire, United Kingdom GlaxoSmithKline Full time

    Position Overview:We are in search of a dedicated, innovative, and detail-oriented scientist with proven expertise in developing sophisticated in vitro systems.The selected candidate will become a key member of the Complex In Vitro Models (CIVM) team within GSK's research division. The primary objective of CIVM is to enhance the predictive and translational...

  • Senior Data Scientist

    3 hours ago

    Stevenage, Hertfordshire, United Kingdom GSK Full time

    About the RoleWe are seeking a highly skilled Senior Data Scientist to join our Non-Clinical Safety (NCS) organization at GSK. As a key member of our team, you will play a critical role in applying cellular and molecular approaches to elucidate mechanisms of toxicity, understand species differences, and identify translational safety biomarkers to inform...

  • Flow Cytometry Technician

    3 weeks ago

    Stevenage, Hertfordshire, United Kingdom PerkinElmer Full time

    Job SummaryWe are looking for highly motivated candidate for the role of Flow Cytometry Technician to build their career and support the PerkinElmer OneSource Scientific Services at one of our customer sites in Stevenage.The successful candidate will be working within the PerkinElmer Extracellular Targeted Cancer Therapies team, who will be responsible for...

  • Automation Applications Specialist

    2 months ago

    Stevenage, Hertfordshire, United Kingdom PerkinElmer Full time

    Job Purpose:The successful candidate will join the Perkin Elmer team working with the GSK Medicine Design automation group to provide first line software and technical support for automated liquid handling, and bench-top automation platforms, enabling minimal equipment downtime and maximal system utilisation. The Automation Applications Specialist will be...

  • Scientific Investigator

    3 days ago

    Stevenage, UK, Hertfordshire, United Kingdom Undisclosed Full time

    Scientific Investigator - Respiratory BiologyScientific Investigator - Respiratory BiologyThe location of the role is Stevenage. The duration of the contract is 12 months (maternity cover). The pay rate on offer is £25.64 per hour (via PAYE). 37.5 hours per week. Role SummaryAre you energised by the challenge of building and shaping the biology on a drug...

  • Lead Biologist

    24 hours ago

    Stevenage, Hertfordshire, United Kingdom Undisclosed Full time

    Job SummaryWe are seeking a highly skilled Senior Research Scientist to join our Respiratory and Immunology Research Unit as a Lead Biologist in our Drug Discovery Program. The successful candidate will be responsible for designing and delivering on the biology strategy as one component of an advanced drug discovery program.Key ResponsibilitiesDevelop and...

  • Flow Cytometry/Immunologist Expert

    3 months ago

    Stevenage, Hertfordshire, United Kingdom GlaxoSmithKline Full time

    Site Name: UK - Hertfordshire - StevenagePosted Date: Apr 4 2023Flow Cytometry / Immunologist ExpertWe are seeking a highly motivated scientist with experience in immunology/ immune oncology to join the Digital Biology Twin (DBT) lab in GSK. DBT has been newly set up in order to help clinical development for further pipelines and to contribute to preclinical...

  • Exosome DNA/Protein Specialist

    4 weeks ago

    Stevenage, Hertfordshire, United Kingdom GlaxoSmithKline Full time

    Site Name: UK - Hertfordshire - StevenagePosted Date: Apr 4 2023Exosome DNA / Protein SpecialistWe are seeking for a highly motivated scientist with experience in extracellular vesicles (i.e. exosome) isolation and characterization to join the Digital Biology Twin (DBT) lab in GSK. DBT has been newly set up in order to help clinical development for further...

  • Patient Derived Organoid Specialist

    3 months ago

    Stevenage, Hertfordshire, United Kingdom GlaxoSmithKline Full time

    Site Name: UK - Hertfordshire - StevenagePosted Date: Apr 4 2023Patient Derived Organoid SpecialistWe are looking for a highly motivated scientist with experience in oncology and cellular biology to join the Digital Biology Twin (DBT) lab in GSK. DBT has been newly set up in order to help clinical development for further pipelines and to contribute to...

  • Scientific Researcher

    5 hours ago

    Stevenage, Hertfordshire, United Kingdom Undisclosed Full time

    Job SummaryWe are seeking a highly skilled Scientific Investigator to join our Respiratory and Immunology Research Unit. As a key member of our team, you will be responsible for designing and delivering on the biology strategy as one component of an advanced drug discovery program.Key ResponsibilitiesDevelop and Enhance Analytical Platforms: Successfully...