Postdoctoral Researcher in Thrombosis Research

4 weeks ago

Hull, Kingston upon Hull, United Kingdom University of Hull Full time

Applicants are required to submit a current CV and cover letter.

This is a 36-month project funded by the British Heart Foundation focussing on the role of platelets in the cardiovascular comorbidities associated with Diabetes. The project will take place within the laboratory of Dr Giordano Pula within the Biomedical Insititute for Multimorbidity (BIM) of the Hull York Medical School (HYMS) at the University of Hull. This study will focus on human platelets and will utilise clinical samples from the Allam Diabetes Centre of the Hull Royal Infirmary (HRI) obtained under the supervision of Prof Thozhukat Sathyapalan. This project is part of a collaboration with the Institute for Cardiovascular and Metabolic Research (ICMR) of the University of Reading, where a second postdoctoral scientist under the supervision of Prof Jon Gibbins will perform complementary experiments focusing on the role platelet in thrombotic complication of diabetes. This collaborative and multidisciplinary job opportunity was funded by the British Heart Foundation a Special Project Grant entitled "Plasma microvesicles cause diabetes-dependent platelet hyperactivity and thrombosis (MV-DISPLAY)" (SP/F/24/

This position requires the ability to work in a multidisciplinary and multicentre team. In addition to coordinating the collection of clinical samples within the Allam Diabetes Centre of the HRI, the postdoctoral scientist holding this position will handle human blood samples to obtain information regarding the alteration of platelet biochemistry and physiology occurring in diabetes. A variety of cell biology techniques (ranging from live cell imaging to flow cytometry to in vitro vascular modelling) and biochemistry approaches (ranging from immunoblotting to second messenger analyses and oxidative stress analyses) will be applied. In addition, clinical material will be utilised to prepare samples to send to our collaborators at the University of York for proteomics studies and to the University of Reading for functional and cell signalling-dedicated experiments. The ability to maintain records of the experiments, analyse and interpret experimental data, and summarise them in oral and written communications for publication will be essential for success in this role. Highly ambitious candidates aiming to start a successful academic career in cardiovascular biology will be prioritized.

The terms of the grant that fund this position require that employment commences no later than 01 / 10 / 2024.

To discuss this role informally, please contact Dr Giordano Pula (HYMS/BIM),

Further details:

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At the University of Hull, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world's talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UoH workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and women particularly for our Grade 9 and 10 roles.

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