Research Associate

1 month ago

Oxford, Oxfordshire, United Kingdom University of Cambridge Full time

We are looking for a highly motivated, proactive and enthusiastic postdoc to work on a Wellcome Trust funded project within the Galliano laboratory the University of Cambridge. Our research focuses on investigating how brain cells change in response to altered sensory inputs, and how such changes in brain cells underpin adaptation, learning and memory at the behavioural level. We use mice as model systems, and we probe the brain networks that encode their sense of smell. We are an inclusive, diverse and welcoming group, invested in open-science and outreach, and committed to mentoring and supporting the career development of all members.

You will lead a project investigating how changes in sensory input (such as olfactory deprivation, enrichment, and learning) prompt adaptive and associative plasticity in neurons within the olfactory bulb. This project will employ advanced optical techniques, including 2-photon microscopy and holographic light shaping, to monitor and manipulate neural activity in vivo. The aim is to elucidate how sensory inputs drive different mechanisms of neuronal plasticity in different cell types, and how interactions among different types of neurons enhance circuit output and information transfer to the cortex.

The successful candidate will have:

  • PhD in Neuroscience or a related field (or be about to receive one)
  • Substantial expertise in either in vivo recording techniques (imaging or physiology) in vertebrates, or a strong background in optics, holographic light shaping, and advanced imaging techniques, particularly 2-photon microscopy
  • Strong analytical skills and proficiency in quantitative analysis of large datasets.
  • Proven track record of research leadership, as demonstrated by preprint(s) or published article(s).
  • Specific examples of excellent communication skills and the ability to work collaboratively within a research team.
  • Specific examples of strong problem-solving abilities and instances demonstrating the capability to work independently as well as within a team.
  • Desirably have a background in sensory systems and plasticity research, experience in mouse behavioural testing, familiarity with tool development (e.g., olfactometers), and cranial window surgeries.

Appointments will be made on a fixed-term, full-time basis for 4 years in the first instance. We are open to discussing various patterns of part-time work to accommodate individual circumstances and/or caring responsibilities. The start date is flexible, but ideally, we would like the position to commence in January 2025.

To ensure your application is as strong as possible, please follow the instructions carefully. Candidates should upload a CV (maximum 3 pages) and a cover letter addressing the following points:

  • Why you want to join our lab and lead this project.
  • How you align with the lab's values and philosophy, found here
  • How this position will serve as a valuable stepping stone for your career.
  • How your previous experience has prepared you for the technical demands of this role. If you lack direct experience, please explain how you plan to acquire the necessary skills, noting that the PI is the only team member with relevant in vivo imaging experience to assist you.
  • Your (brief) thoughts on the most interesting and yet unanswered questions in the fields of plasticity and olfaction.

Ensure that your CV and cover letter together address all these criteria. Please also include the contact details of two professional referees.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

£36,024 to £44,263 pa

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