Senior Principal Engineer

7 days ago

Brentford, Greater London, United Kingdom GlaxoSmithKline Full time
Site Name: UK - London - Brentford, Bangalore, Irvine, Poznan Pastelowa, UK - Hertfordshire - Stevenage, UK - Hertfordshire - Ware, Warsaw Rzymowskiego 53
Posted Date: Apr 9 2024

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.

Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK

Senior Principal Engineer - Graph

As the Senior Principal Engineer, you will be part of GSK's ambitious programme to transform its commercial manufacturing and supply chain organisation helping to increase capacity and speed for transferring new products from our R&D organisation. Data and AI are an essential part in achieving this goal, which ultimately will help launch medicines quicker and have a positive impact on patients.

We are open for this role to be based at GSK House, Stevenage, Ware, Irvine, Poznan, Warsaw and Bangalore.

We're moving towards a more sustainable future with our new headquarters. With better public transport links and proximity to world-class science and technology institutions, we're excited for our move to the vicinity of Earnshaw Street, London WC1A ("the New HQ") by end H1 2024.

Job Purpose

The primary purpose of this role is to take technical accountability for the CMC Knowledge Graph, driving forward its design and implementation through being hands-on and by providing technical direction and oversight to rest of the development team, while also working closely with Product Management, business representatives and other Tech & Data experts to ensure that it meets the business requirements.

More broadly, the role will additionally:
  • Support the CMC Knowledge System Director, product managers, business leaders and other stakeholders to identify opportunities where Knowledge Graph and other Data & AI capabilities can have a transformative impact on GSK's CMC and New Product Introduction (NPI) processes
  • Provide technical leadership for other Data & AI Products in the CMC/NPI portfolio
The immediate priority in the role is to drive the technical work needed to productionise an existing proof-of-concept CMC Knowledge Graph and its associated analytics use-cases into a full-fledged, sustainable, supportable Data & AI Product.

In this role you will...
  • Lead the ongoing technical design, development, testing and release of the CMC Knowledge Graph and other Data & AI solutions in CMC/NPI portfolio
  • Provide leadership, technical guidance, and mentorship to development team (both internal staff and contractors), driving performance and continuous improvement, including identifying and realising opportunities to increase velocity
  • Use hands-on technical problem-solving expertise to address technical challenges throughout product life-cycle
  • Support Product Management in creating and evolving a compelling Product vision and roadmap, using expertise and insights on the art-of-the-possible as well as in engaging users and other business stakeholders to gather feedback and identify system enhancements
  • Collaborate with Data & AI Architecture team and other stakeholders to ensure alignment with established architecture standards, contributing to and evolving them to incorporate new technologies and patterns as needed
  • Ensure compliance with relevant policies and procedures (including GxP validation where required)
  • Provide input to, reviewing and approving key technical documents (e.g. design spec, validation plan)
  • Stay updated with the latest advancements in Knowledge Graph and related technologies, recommending and implementing improvements to enhance system functionality and performance.
  • Lead discovery / proof-of-concept activities to establish early technical feasibility of new Products or Product Features
Why you?
Basic Qualifications/Experience:

We are looking for professionals with these required skills to achieve our goals:
  • Strong technical expertise in designing, developing, and supporting Knowledge Graphs, including proficiency in working with RDF graph technologies, preferably Azno.
  • Proven track record in delivering complex data engineering projects in a cloud environment, preferably Azure.
  • Experience in leading and managing technical teams
  • Expertise in data modelling/ontologies, data integration, and data transformation techniques.
  • Strong programming skills and proficiency in utilising code repositories, such as Git, for efficient version control, collaboration, and code management.
  • Experience with DevOps principles and CI/CD practices to automate software delivery, streamline development processes, and ensure efficient deployment and monitoring
Preferred Qualifications/Experience:

If you have the following characteristics, it would be a plus:
  • Understanding of pharmaceutical industry data and domain knowledge within CMC.
  • Knowledge of GxP compliance requirements and experience implementing them in data engineering projects
Please take a copy of the Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above.

The information that you have provided in your cover letter and CV will be used to assess your application.

Why Us?

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organization where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to positively impact the health of 2.5 billion people by the end of 2030.

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on or

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive .

As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it. Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.

We're moving towards a more sustainable future with our new headquarters. With better public transport links and proximity to world-class science and technology institutions, we're excited for our move to the vicinity of Earnshaw Street, London WC1A ("the New HQ") by end H1 2024.

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