Research Technician
2 weeks ago
About the role
RLBP1 is a gene that encodes cellular retinaldehyde binding protein 1 (CRALBP), a 36-kD protein involved in the visual cycle. When the gene is not functional due to genetic changes, it results in a retinal degeneration. Patients experience a prolonged dark adaptation, reduced light sensitivity and progressive loss of vision. Mutations in this gene are known to cause differing phenotypes including retinitis pigmentosa (RP), retinitis punctata albescens, Bothnia-type dystrophy, Newfoundland rod-cone dystrophy, and fundus albipunctatus. RLBP1 is a rare inherited retinal disorder (IRD) with fewer than cases appearing in published research. There is no therapeutic intervention that can slow disease progression or restore sight.
We are looking to appoint a Research Technician to join the Moosajee Laboratory investigating the development of non-viral approaches, using mRNA and non-viral gene therapy, as potential treatment options for RLBP1-retinopathy. The Research Technician will provide technical support on day-to-day laboratory duties such as maintaining cell cultures, prepare stocks and reagents, ensure safety protocols are accurate and up-to-date, maintain equipment, routine molecular biology and maintenance of databases.
Additional duties include performing retina histology ( sectioning, immunohistochemistry, in situ hybridization). The post holder is also expected to learn new techniques / skills on the job.
DBS
Due to the nature of the role, an Enhanced Disclosure and Barring Service (DBS) check is required for this post. Any offer of employment will be subject to a DBS check.
About you
The candidate must be a good communicator, both in lay and scientific terms, with strong writing skills. They must be competent with literature searches, have background understanding of genetic eye disease, ideally having seen patients clinically and being aware of their management and needs. The candidate should be organised, hardworking and enjoy writing.
What we offer
Working with some of the greatest intellects in the world, UCL also offers a generous pension scheme and holiday allowance, plus closure and bank holidays as well as enhanced parental pay and more.
-
Research Technician
3 weeks ago
London, United Kingdom Imperial College London Full timeThe Barry lab in the Department of Metabolism, Digestion and Reproduction is seeking to appoint a Research Technician in Cancer Biology and Gut Health to support a UKRI-funded project focused on studying active hydrolases and hydrolase regulators in colorectal cancer using ‘omics’ and advanced gut-culture models. The successful candidate will play a...
-
Research Technician
1 week ago
London, United Kingdom Imperial College London Full timeGBS diseases are a major cause of morbidity and mortality in humans. The molecular basis and infection processes of these diseases remain to be fully determined. We strive to decipher the molecular processes that drive GBS to cause adult invasive, principally the mechanisms utilised to evade and/or manipulate the immune responses.We are seeking a...
-
Research Technician
5 days ago
London, United Kingdom Imperial College London Full timeWe are looking for a part-time Research Technician to join the cardiovascular proteomics research group (),led by Professor Manuel Mayr at the newly established laboratory at the Sir Michael Uren Hub, Imperial White City Campus. Prof Mayr’s group has extensive experience in proteomics and state-of-the art mass spectrometry equipment.Our research spans a...
-
Research Technician
1 month ago
London, United Kingdom Imperial College London Full timeApplications are invited for a Research Technician post in Reproductive Immunology/Virology to work on a multi-year NIH-funded research project. The overall aim of the project is to investigate the role of placental macrophages in cytomegalovirus infection at the maternal-fetal interface. The post includes the opportunity to perform, and gain experience in a...
-
Senior Research Laboratory Technician
5 days ago
London, United Kingdom Imperial College London Full timeThe Department of Mechanical Engineering is seeking a Senior Research Laboratory Technician to support research activities within the Thermofluids Division. A world leading expert in combustion, heat & mass transfer, fluid flow, turbo machinery, and next generation & novel fuels, this position will support our diverse and expert team of Academic and...
-
Laboratory and Insectary Research Technician
2 weeks ago
London, United Kingdom Imperial College London Full timeWe are seeking to appoint a Research Technician to join a project that aims to build and improve gene drive systems, based on the use of CRISPR/Cas9 expressed in the germline of the mosquito vectors of malaria, with the ultimate goal of malaria control by decreasing the reproductive potential of mosquito populations. You will perform cloning, molecular...
-
Senior Research Pharmacy Technician
1 week ago
London, United Kingdom University College London Hospitals NHS Foundation Trust Full timeJob summary University College London Hospitals (UCLH) undertakes world-class research across many specialities including early phase, cancer, haematology, and neurology. As a senior research pharmacy technician (or Science Manufacturing Technician) you will be part of the pharmacy clinical trials team facilitating this research. Your key role is to...
-
Research Animal Technician
6 days ago
London, Greater London, United Kingdom Hobson Prior Full timeWe are seeking an experienced Animal Technician to join our team for a 12-month maternity cover role at a leading biotech company in Central London. The successful candidate will be responsible for conducting research and development activities, specifically focusing on animal procedures to assess vision in mouse models of retinal disease.Main...
-
Digital Print Technician
6 days ago
London, Greater London, United Kingdom Social Sciences and Humanities Research Council Full timeAbout the Role:We are seeking a talented Digital Print Technician to join our team at the Social Sciences and Humanities Research Council. In this role, you will be responsible for assisting with various digital print-related tasks, including color matching, metal work, and finishing banners.Responsibilities:• Assisting with color matching and ensuring...
-
Vision Research Technician
6 days ago
London, Greater London, United Kingdom Hobson Prior Full timeJob DescriptionHobson Prior is seeking an experienced animal technician to join our team as a vision research specialist.About the RoleYou will have at least 2-3 years' experience of working with laboratory animals, preferably with mice.You will be responsible for performing animal procedures to assess vision in mouse models of retinal disease.Key...
-
Research Facility Senior Technician
1 month ago
London, United Kingdom UCL Eastman Dental Institute Full timeAbout the role The HCBF is a high-throughput screening facility located at the Laboratory for Molecular Cell Biology with the main aim to facilitate research projects using high content, image- and non-image-based, screening involving technologies such as RNAi and CRISPR, as well as drug discovery projects using small molecule compound libraries. We...
-
Research Technician
7 days ago
London, Greater London, United Kingdom undisclosed Full timeJob Description**Collaborative Research Opportunity**We are seeking a highly motivated Laboratory Research Scientist to join our team at the Crick Institute. As a key member of our laboratory, you will play a crucial role in supporting our research projects and contributing to the success of our team.**Key Responsibilities**Collaborate with laboratory...
-
Scientific Research Associate
3 weeks ago
London, Greater London, United Kingdom Imperial College London Full timeJob Title: Research TechnicianThe Department of Metabolism, Digestion and Reproduction at Imperial College London invites applications for a Research Technician position in Cancer Biology and Gut Health. The successful candidate will play a key role in supporting the Principal Investigator and collaborating with researchers in the Barry team and partnering...
-
London, United Kingdom Orchard Therapeutics Full timeLocation: London, UKReporting to: Principal/ Senior Scientist in Translational ResearchJob summaryOrchard Therapeutics is a pioneering company in the field of cell and gene therapy with an immediate opportunity for a highly motivated and proactive Research Technician who ideally has experience in working with Viral Vectors for gene delivery to join...
-
Technical Research Specialist
3 weeks ago
London, Greater London, United Kingdom UCL Eastman Dental Institute Full timeAbout the RoleThe UCL Eastman Dental Institute is looking for a skilled Research Technician to join the Isaacs Lab team. Our team is dedicated to developing new gene therapy approaches for FTD/ALS, and we are seeking a highly motivated individual to work on pathological analysis and biomarker development for a treatment being tested in mouse models of...
-
Workshop Technician
1 month ago
London, United Kingdom Imperial College London Full timeThe Department of Mechanical Engineering, Imperial College London, is seeking a Workshop Technician to join its Research Design and Manufacturing (RDM) facility. Supporting the ground-breaking research undertaken across the Departments Academic disciplines, the RDM Workshop team is a key component in our research having real-world impacts on commercial,...
-
Workshop Technician
1 month ago
London, United Kingdom Imperial College London Full timeLocation: South Kensington About the role: The Department of Mechanical Engineering, Imperial College London, is seeking a Workshop Technician to join its Research Design and Manufacturing (RDM) facility. Supporting the ground-breaking research undertaken across the Departments Academic disciplines, the RDM Workshop team is a key component in our research...
-
Sato - Research Pharmacy Assistant
6 months ago
London, United Kingdom University College London Hospitals NHS Foundation Trust Full timeUCLH is committed to delivering top-quality patient care, excellent education, and world class research. Our Trust values are Safety, Kindness, Improving and Teamwork. As a research pharmacy assistant, you will be assisting our pharmacy clinical trials team deliver world class research by maintaining the storage and receipt of clinical trials medicines...
-
Postdoctoral Researcher
3 days ago
London, United Kingdom 丽水学院 Full timeJob Description We are seeking outstanding, enthusiastic, and innovative-thinking global talents who are committed to research and teaching excellence to fill multiple tenure-track or tenured faculty positions. Faculty positions are open at four ranks: Assistant Professor, Associate Professor, Full Professor, and Chair Professor. Research disciplines at...
-
Senior Research Technician
4 days ago
London, United Kingdom UCL Eastman Dental Institute Full timeAbout the role We are now recruiting a Senior Research Technician to establish and develop the collection, processing, storage, and analysis of biological samples within the existing longitudinal biobanking projects at UCL. You will be key to the main aim to use biological substrates that can be collected during disease progression to monitor disease...