Clinical Research Associate in the Cancer Cachexia

4 weeks ago


Cambridge, United Kingdom University of Cambridge Full time

We are looking for a talented clinician to join a multidisciplinary team of clinical and basic scientists investigating the drivers of cancer cachexia.

This post represents an excellent opportunity for a medically qualified trainee (oncology, endocrinology or metabolism) to play a key role in undertaking human based studies, including detailed analysis of food intake and energy expenditure in a naturalistic setting.

There will also be opportunity to be involved in molecular and immunological laboratory analysis related to this project.

The team includes oncologists, endocrinologists and psychiatrists looking to focus their established experience in understanding disorders of body weight onto the problem of weight loss in cancer.

Our hypothesis is that molecular signals from the tumour itself, activating and interacting with neuroendocrine pathways in particular, are major drivers of the anorexia, systemic sickness and tissue wasting seen in cachexia.

We are part of the "CANcer Cachexia Action Network" (CANCAN) group, a US/UK consortium funded by Cancer Grand Challenges, a major initiative co-funded by Cancer Research UK and the National Cancer Institute in the US.

The post is ideally suited to clinicians who have already some previous experience in these areas but this is not essential. The primary supervisor will be Dr Anthony Coll (Clinical Biochemistry/Institute of Metabolic Science) working closely with Dr Claire Connell (CRUK) and Professor Paul Fletcher (Psychiatry).The work will be carried out on a number of facilities on the Cambridge Biomedical Campus.

The successful applicant will ideally have previous research experience and knowledge of Good Clinical Practice (GCP) is expected

Fixed-term: The funds for this post are available until June 2027 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment. This appointment also requires an Honorary Clinical Contract.

This is an integrated appointment between the University and Cambridge University Hospitals NHS Foundation Trust ("NHS Trust"). You will therefore also be issued with an Honorary Clinical Contract by the NHS Trust. You should be aware that if your contract with the NHS Trust is terminated your employment with the University will be terminated, and vice versa.

Closing date: 9 June 2024

Date of interview: To be confirmed

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.



  • Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full time

    We are looking for a talented clinician to join a multidisciplinary team of clinical and basic scientists investigating the drivers of cancer cachexia.This post represents an excellent opportunity for a medically qualified trainee (oncology, endocrinology or metabolism) to play a key role in undertaking human based studies, including detailed analysis of...


  • Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full time

    We are looking for a talented clinician to join a multidisciplinary team of clinical and basic scientists investigating the drivers of cancer cachexia.This post represents an excellent opportunity for a medically qualified trainee (oncology, endocrinology or metabolism) to play a key role in undertaking human based studies, including detailed analysis of...


  • Cambridge, United Kingdom University of Cambridge Full time

    We are looking for a talented clinician to join a multidisciplinary team of clinical and basic scientists investigating the drivers of cancer cachexia. This post represents an excellent opportunity for a medically qualified trainee (oncology, endocrinology or metabolism) to play a key role in undertaking human based studies, including detailed analysis of...


  • Cambridge, United Kingdom University of Cambridge Full time

    We are looking for a talented clinician to join a multidisciplinary team of clinical and basic scientists investigating the drivers of cancer cachexia. This post represents an excellent opportunity for a medically qualified trainee (oncology, endocrinology or metabolism) to play a key role in undertaking human based studies, including detailed analysis...


  • Cambridge, United Kingdom University of Cambridge Full time

    We are looking for a medically qualified trainee in oncology to join an established, multidisciplinary team investigating cancer cachexia. The post has an essential requirement for an experienced clinician with significant oncology clinical training, who also has experience in participant recruitment and a strong knowledge of "Good Clinical Practice" as it...

  • Scientific Associate

    4 weeks ago


    Cambridge, United Kingdom Cancer Research UK Cambridge Institute Full time

    Europe’s top cancer charity, Cancer Research UK, has combined with the University of Cambridge to fund the world class Cancer Research UK Cambridge Institute, situated on Addenbrooke’s Biomedical Campus in Cambridge. As part of the University Of Cambridge School Of Clinical Medicine, the Institute’s research ranges from basic cancer biology through...

  • Scientific Associate

    2 weeks ago


    Cambridge, United Kingdom Cancer Research UK Cambridge Institute Full time

    Europe’s top cancer charity, Cancer Research UK, has combined with the University of Cambridge to fund the world class Cancer Research UK Cambridge Institute, situated on Addenbrooke’s Biomedical Campus in Cambridge. As part of the University Of Cambridge School Of Clinical Medicine, the Institute’s research ranges from basic cancer biology through...


  • Cambridge, United Kingdom University of Cambridge Full time

    This post is an outstanding opportunity for an early career oncologist wishing to develop an independent research programme within our internationally leading translational research and clinical trial portfolio in women's cancers. You will have recently completed your specialist training in medical oncology and can demonstrate strong experience in the...

  • Senior Scientist

    4 days ago


    Cambridge, United Kingdom Cancer Research UK Full time

    At Cancer Research UK, we exist to beat cancer . Are you a passionate Scientist looking for the opportunity to work on exciting drug discovery projects at the world’s leading cancer research charity? This could be the perfect opportunity to utilise your expertise in a cause-driven environment helping Cancer Research to beat cancer sooner. About the...

  • Procurement Manager

    2 weeks ago


    Cambridge, United Kingdom Cancer Research UK Cambridge Institute Full time

    In 2013, Europe’s top cancer charity, Cancer Research UK, combined with the University of Cambridge to fund the world class Cancer Research UK Cambridge Institute, situated on the Addenbrooke’s Biomedical Campus in Cambridge. As part of the University of Cambridge School of Clinical Medicine, the Institute’s research ranges from basic cancer biology...

  • Procurement Manager

    2 weeks ago


    Cambridge, United Kingdom Cancer Research UK Cambridge Institute Full time

    In 2013, Europe’s top cancer charity, Cancer Research UK, combined with the University of Cambridge to fund the world class Cancer Research UK Cambridge Institute, situated on the Addenbrooke’s Biomedical Campus in Cambridge. As part of the University of Cambridge School of Clinical Medicine, the Institute’s research ranges from basic cancer biology...


  • Cambridge, United Kingdom University of Cambridge Full time

    This post is an outstanding opportunity for an early career oncologist wishing to develop an independent research programme within our internationally leading translational research and clinical trial portfolio in women's cancers. You will have recently completed your specialist training in medical oncology and can demonstrate strong experience in the...

  • Research Associate

    2 months ago


    Cambridge, United Kingdom University of Cambridge Full time

    We are focussed on developing accurate and scalable tests that could make a significant contribution to reducing the number of cancer deaths. We are looking for a data analyst or computational biologist with experience of analysing biological data to join our multi-disciplinary cancer research team, develop our cutting-edge bioassay, and transform the lives...


  • Cambridge, United Kingdom Cancer Research UK Cambridge Institute Full time

    The Cancer Research UK Cambridge Institute (CRUK CI) focuses on tackling questions relating to cancer diagnosis, treatment and prevention, supported by world-class technology platforms. Our aim is to be a focus for the practical application of high-quality basic research, forming a bridge between the world-class science of the University of Cambridge and...


  • Cambridge, United Kingdom Cancer Research UK Cambridge Institute Full time

    In 2013, Europe’s top cancer charity, Cancer Research UK, combined with the University of Cambridge to fund the world class Cancer Research UK Cambridge Institute, situated on the Addenbrooke’s Biomedical Campus in Cambridge. As part of the University of Cambridge School of Clinical Medicine, the Institute’s research ranges from basic cancer biology...

  • Research Associate

    2 months ago


    Cambridge, United Kingdom University of Cambridge Full time

    An exciting opportunity has arisen to join a new project exploring kidney cancer follow-up. The project is funded by the National Institute for Health Care Research and aims to develop a new resource to support decision-making about follow-up care after surgery for individuals with localised kidney cancer. The project includes the development and validation...

  • Research Associate

    1 week ago


    Cambridge, United Kingdom University of Cambridge Full time

    We are seeking to appoint a postdoctoral researcher to better understand the role of cellular senescence as part of the lung tumour microenvironment and the interplay with ageing. The postdoc will be based in the laboratory of Dr Daniel Munoz-Espin, Group Leader in the Department of Oncology (Early Cancer Institute) at University of Cambridge and co-Director...

  • Research Assistant

    3 weeks ago


    Cambridge, United Kingdom Cancer Research UK Cambridge Institute Full time

    We are looking for a bright and motivated Research Assistant to join our team at the CRUK Cambridge Institute (part of the University of Cambridge) to investigate the mechanisms surrounding cancer initiation, with a particular focus on early stage breast cancer. You will be part of a small team, led by Dr Clare Rebbeck, which studies early events in breast...

  • Research Assistant

    2 weeks ago


    Cambridge, United Kingdom Cancer Research UK Cambridge Institute Full time

    We are looking for a bright and motivated Research Assistant to join our team at the CRUK Cambridge Institute (part of the University of Cambridge) to investigate the mechanisms surrounding cancer initiation, with a particular focus on early stage breast cancer. You will be part of a small team, led by Dr Clare Rebbeck, which studies early events in breast...

  • Research Assistant

    4 weeks ago


    Cambridge, United Kingdom Cancer Research UK Cambridge Institute Full time

    The Creixell laboratory at the CRUK Cambridge Institute (part of the University of Cambridge) is seeking to hire an enthusiastic and highly-motivated Research Assistant to join a team of scientists studying studying protein substrate specificity. Our lab integrates machine learning and high-throughput biochemistry to study how proteins selectively recognise...