Protein Expression Research Assistant

4 days ago

Oxford, United Kingdom Exscientia Full time

We are looking to recruit Research Assistants, in Protein Expression, specialising in cell culture and protein expression to help support our growing group by performing heterologous cell expression. The role will involve facilitating our expansion by helping to develop and run our pipeline for the scaling of recombinant protein expression in both eukaryotic and prokaryotic expression systems. Excited by finding new ways of working, you will be encouraged to bring your own ideas into play where they contribute to the continuous improvement of our protein production platform.

**Responsibilities**:

- Routine cell maintenance and scaling of Insect and Mammalian cell lines.
- Production of recombinant baculovirus.
- Transfection/infection for recombinant protein expression.
- Expression of recombinant proteins in _E. coli_
- Attention to detail including good record keeping.
- To author high quality reports and data summaries.
- To communicate updates to projects.
- To work to the highest scientific standards

**Requirements**:

- Experience in cell culturing techniques in both Mammalian and Insect cell lines. Cell stock maintenance and scale up for protein expression.
- A demonstrable analytical approach to problem solving.
- The ability to work as part of a team.
- Flexible, adaptable and able to work across multiple projects.

**Desirable Competencies & Requirements**
- Experience in growing cells in fermenters/reaction vessels
- Experience of transfection/infection in Insect cells (transient and Baculovirus) and Mammalian cells (transient, BacMam and LentiX).
- Experience in expressing proteins in _E. coli_
- Previous work experience in an industrial or high-throughput environment.
- Demonstrated ability to optimise workflows.
- Experience in working with and adopting complex laboratory automation/liquid handling.
- Experience with LIMS systems.

**Benefits**
- Work together to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI-driven discovery.
- We will work with you to kick-start or further grow your career - from funding for professional development and conference attendance. To the opportunity to acquire valuable skills, work on problems that matter, and learn from world-class technological and scientific leaders.
- Opportunity to join an inclusive, collaborative and intellectually stimulating culture
- We will work with you to provide a highly competitive compensation as we continue to grow and thrive.
- Our team’s health and well-being is important to us we offer a generous holiday allowance, provide flexible working and remote working to encourage all of our team to manage their own work, time and life along with wellbeing and mindfulness support.
- When you are in the office, you will have access to a kitchen stocked with an endless supply of food for all employees. Along with access plenty of break out areas so you can get to know the people you are working with. Some of the best ideas start with a coffee break
- Hear from our team why they enjoy working here

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