Post-doctoral Research Associate
4 days ago
**Post-Doctoral Research Associate**
**The Opportunity**:
An exciting postdoctoral position is available to research the role of epigenetic dysregulation in carcinogenesis.
We are looking for a self-motivated, enthusiastic research fellow to join the laboratory of Dr Duncan Sproul at the University of Edinburgh’s Institute of Genetics and Cancer to understand the role of heterochromatin hypomethylation in carcinogenesis. This project is a close collaboration with Kevin Myant’s laboratory based within the same institute.
We have recently shown that the DNA methyltransferase DNMT3B is required to maintain heterochromatic DNA methylation in colorectal cancer cells (Taglini _et al _. 2024, EMBO Reports **25**:1130, DOI: 10.1038/s44319-024-00061-5). Our new project will use this insight as a tool to understand the role of heterochromatin hypomethylation in colorectal carcinogenesis where DNMT3B is a tumour promoting gene (Lin _et al _2006, Molecular and Cellular Biology 26:2976, DOI: 10.1128/MCB.26.8.2976-2983.2006).
The post is full-time (35 hours per week) and fixed term - funding is available from 1 st May 2025 for 3 years pending review after 6 months.
The salary for this post is UE07 £40,247 to £47,874 per annum
Further details of work from the Sproul and Myant groups are available at:
**Click**here **to view a copy of the**full job description **.**
**The Institute of Genetics and Cancer**
The Institute of Genetics and Cancer is an international research institute that is part of the University of Edinburgh and is located on the Western General Hospital campus. It hosts 70 research groups and over 500 scientists, support staff, fellows, PhD students and visiting scientists. The institute has a strong culture of collaboration, interaction and mentoring diverse careers.
**As a valued member of our team you can expect**:
- A competitive salary
- An exciting, positive, creative, challenging and rewarding place to work.
- To be part of a diverse and vibrant international community
- Comprehensive Staff Benefits, such as a generous holiday entitlement, competitive pension schemes, staff discounts, and family-friendly initiatives. Check out the full list on our **staff benefits page**(opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits
**Championing equality, diversity and inclusion**
The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.
Prior to any employment commencing with the University of Edinburgh you will be required to evidence your right to work in the UK. Further information is available on our **right to work webpages**(opens new browser tab)
On this occasion the University will not consider applicants requiring sponsorship for this role. International workers will therefore only be able to take up this role if they can demonstrate an alternative right to work in the UK.
**Application details**
Interviews will be held during the week beginning 10 th March 2025. Following the interview, the successful applicant will have the opportunity to visit the Institute of Genetics and Cancer.
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