Research Associate

5 days ago

Hammersmith, United Kingdom Imperial College London Full time

Job number

**MED05281**
- Faculties

**Faculty of Medicine**
- Departments

**Department of Brain Sciences**
- Salary or Salary range

**£49,017 - £57,472 per annum**
- Location/campus

**Hammersmith Campus - Hybrid**
- Contract type work pattern

**Full time - Fixed term**
- Posting End Date

**24 Sep 2025**

**About the role**:
The Owen and Barnes labs are recruiting a Postdoctoral Research Associate (PDRA) for two years, with the possibility of extension for a further two years. The role involves using a range of in vitro and in vivo approaches to investigate how knockout and drug inhibition of the mitochondrial protein TSPO protects against vascular dysfunction in early-stage Alzheimer’s disease.

**What you would be doing**:
Building on positive results in rodent models, we are running a clinical study to test the effect of a TSPO ligand on cerebrovascular function in individuals with early Alzheimer’s disease. The focus of this project is to understand the mechanism by which TSPO ligands protect the vasculature. The postholder will collect and analyse data using various in vitro and in vivo approaches. A background in cellular biology and data analysis is essential, and knowledge of neuroscience, vascular biology or mitochondrial biology would be an advantage.

**What we are looking for**:
We are seeking a highly motivated researcher with expertise in neuroscience, vascular biology or mitochondrial biology, who wishes to use this position as a platform towards securing a nationally competitive fellowship.

**What we can offer you**:

- Access to state-of-the-art equipment and infrastructure
- Networking and international travel opportunities
- The opportunity to advance your career at a world-leading institution, contributing to science with real impact
- A sector-leading salary and remuneration package (including 39 days annual leave and a generous pension scheme)
- A wide range of workplace benefits, including flexible working from day one, comprehensive family leave packages, on-site leisure facilities and a cycle-to-work scheme
- Interest-free season ticket loans for travel
- An inclusive, collaborative, and diverse workplace culture, supported by staff networks and resources to promote personal and professional wellbeing

**Further information**:
This is a Full time fixed term role, based at our Hammersmith Campus.

**Available documents**:

- Attached documents are available under links. Clicking a document link will initialize its download.- Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities mentioned above.

**About Imperial**:
Welcome to Imperial, a global top ten university where scientific imagination leads to world-changing impact.

Join us and be part of something bigger. From global health to climate change, AI to business leadership, here at Imperial we navigate some of the world’s toughest challenges. Whatever your role, your contribution will have a lasting impact.

As a member of our vibrant community of 22,000 students and 8,000 staff, you’ll collaborate with passionate minds across nine London campuses and a global network.

This is your chance to help shape the future. We hope you’ll join us at Imperial College London.

**Our Culture**:
Our values are at the root of everything we do and everyone in our community is expected to demonstrate respect, collaboration, excellence, integrity, and innovation.

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