Senior Bioprocess Specialist
1 week ago
You will join our Production team in London, operating mammalian tissue culture systems to support the production of cultivated fat. You will implement novel protocols and technologies to drive our progress towards large-scale manufacturing, working alongside brilliant engineers, biologists, and mathematicians.
As a Senior Bioprocess Specialist, you will work within our Production team and be the key hands-on specialist running pilot scale bioreactor operations, supporting scale-up and process validation. Over time you will transition into a key role for routine production at the next manufacturing scale. Your diligence, talent for collaboration, and reliability will make you an essential member of our team.
What you'll do
- Operate, monitor, and maintain our in-house-built pilot-scale bioreactors, including set-up, inoculation, sampling, harvest, CIP/SIP, cleaning, and shutdown procedures.
- Execute standard operating procedures (SOPs), batch records, and other documentation, ensuring full compliance with quality and safety standards.
- Troubleshoot process and equipment issues in real time, including sensor faults, flow disruptions, in-process monitoring deviations, and contamination events; perform root-cause analysis and implement corrective actions to maintain bioreactor performance and product quality.
- Support scale-up efforts by assisting in the transfer of pilot-scale protocols and lessons learned into the next-scale bioreactor design and validation.
- Train junior technicians and operators on bioreactor protocols, safety, and SOPs.
What we're looking for
- A master's degree (or equivalent experience) in biotechnology, biochemical engineering, bioprocess engineering, or related life sciences / engineering field
- Minimum 5 years of experience working with microbial or mammalian bioreactors in pilot / lab / manufacturing environment
- Demonstrated ability in leading cell culture operations in a production environment
- Strong technical troubleshooting skills: experience diagnosing and resolving bioprocess upsets
- Excellent aseptic technique in biosafety cabinets
- Experience with control systems (e.g. SCADA, distributed control systems, PLC/HMI) and process automation
- Good analytical skills: experience sampling, performing assays, interpreting process data
- Experience following and writing SOPs, GMP / GLP documentation practices, batch record and deviation reporting
- A talent for teamwork and collaboration
Bonus points for experience with:
- Experience with large scale culture media preparation (+100 L scale)
- Experience with downstream processing methods
- Project management tools
- Electronic Laboratory Notebook (ELN) software
Why join us?
- We're tackling real-world problems through cutting-edge bioreactor technology and sustainable solutions. Join us, and you won't just be doing a job—you'll be shaping the future of food and biotech sustainability.
- Combine deep bioreactor work with troubleshooting skills to meet ambitious scale-up goals in a brand new industry.
- Work with expert bioprocess scale-up, production, hardware team and software teams to implement a novel bioreactor platform for food and biotech. We don't just work together—we grow together.
- Join a fast-paced startup culture that values collaboration, integrity, and shared success.
The benefits:
Highly competitive salary (£55k)
Stock option plan
Brand new lab and office in Old Street
Weekly socials and events
Pension plan (matching up to 5%)
25 days' holiday + bank holidays
Supportive and collaborative environment
Being part of something amazing
About Hoxton FarmsHoxton Farms grow cultivated pork fat, a healthy and delicious ingredient for the food industry. Cofounded in 2020 by Max Jamilly and Ed Steele, we are building the world's most scalable and cost-effective tech stack for mammalian cell biomanufacturing – and we're monetising it with a premium B2B ingredient. Hoxton Farms are a team of 50 based in London. We have raised from investors including Founders Fund, Collab Fund, FSV/F-Prime and Global Brain.
- Healthy fats. B2B cultivated fat is fast to market and will dominate a premium niche. Compared to traditional fat, cultivated pork fat is healthier and more scalable. Hoxton Farms have commercial traction with meat/CPG companies including some of the largest food companies in Asia.
- Cost and scale. Hoxton Farms have patented scalable, low-cost, high-yield bioreactors for mammalian stem cells. We opened a pilot production facility in London in 2023.
- Team. Hoxton Farms have a brilliant and friendly team including world-class talent from the cultivated meat, biotech and engineering industries – all under one roof in central London.
Hoxton Farms is an equal opportunity employer committed to providing a working environment that embraces inclusion, diversity and belonging.
If you believe you would add value to our company but don't meet all the criteria, we would still love to hear from you. We especially encourage applications from female+, LGBTQIA+, disabled and Black, Asian and Minority Ethnic (BAME) candidates, as these groups are underrepresented in the tech industry.
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