Current jobs related to Associate Director, Clinical Operations - Cambridge - Parabilis Med
-
Associate Director, Clinical Operations
16 hours ago
Cambridge, Cambridgeshire, United Kingdom Nuvalent, Inc. Full time $171,000 - $200,000The Company:With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company...
-
Cambridge, United Kingdom AstraZeneca Full timePosition : Associate Director, Clinical Pharmacokineticist Location: Cambridge, UK At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and...
-
Clinical Programs Operation Director
6 days ago
Cambridge, United Kingdom CK GROUP Full timeCK Group are recruiting for a Global Clinical Programs Operation Director to join a company in the Pharmaceutical industry at their site based in Cambridge with some flexibility on remote working, on a contract basis for 12 months. **Daily Rate**: Per Day £700-750 LTD **Hours of work or shifts**: Monday to Friday 37.5 hours a week. **Essential...
-
Director/associate Director of QA
2 weeks ago
Cambridge, United Kingdom Healx Full time**Start Date**: Negotiable **About Healx** There are 7,000 known rare diseases that affect 400 million people across the globe, and 95% of them have no approved treatment. We’re on a mission to change that. **Our Values** **Care for Rare - **Rare disease patients are at the heart of what we do **Grow as individuals - **We are learners always seeking...
-
Clinical Trial Associate
1 week ago
Cambridge, United Kingdom Bicycle Therapeutics Full timeCompany Description Bicycle Therapeutics (NASDAQ: BCYC) is a clinical-stage biopharmaceutical company developing a novel class of medicines. Our pipeline includes Bicycle Toxin Conjugates® as well as fully synthetic Bicycle® systemic immune cell agonists and Bicycle tumor-targeted immune cell agonists (Bicycle TICAs) focused on oncology indications with...
-
Senior Clinical Operations Associate
2 weeks ago
Cambridge, United Kingdom Park Street People Full time**An innovative global pharmaceutical company is currently looking for a Senior Clinical Operations Associate to join their team on an initial 12-month contract as the business continues to grow their portfolio.** As an integral part of the team, you will be supporting the operational execution of Investigator Sponsored Studies (ISS) from its planning to...
-
Associate Director of Nursing
8 hours ago
Cambridge CB EF, United Kingdom NHS Full timeWe are seeking an enthusiastic/experienced senior nurse to be our Associate Director of Nursing & Quality (ADNQ) for the Adults and Specialist Mental Health (ASMH) Directorate. You will lead the nursing workforce and on quality across our Directorate to ensure we provide a high-quality service, deliver great service user and carer experience and meet all...
-
Associate Director of Estates
6 days ago
Cambridge, United Kingdom MMP Consultancy Limited Full timeMMP Consultancy is seeking an Associate Director of Estates and Facilities on behalf of an NHS Trust based in Cambridgeshire. The Associate Director of Estates and Facilities' key responsibilities for the role include: - Contribute to ensuring that the Trust's corporate objectives are achieved with a specific focus on providing safe and secure premises and...
-
Associate Director of Estates and Facilities
2 weeks ago
Cambridge, United Kingdom Your World Healthcare Full time**Associate Director of EstatesandFacilities** **Location**:Cambridge **Job Type**: InteriM/Fixed Term / Permanent **Proposed start date**: Immediate **Band**: 8D **Sector**: Healthcare **Base**:Hospital **Pay Rates**: £38.50- £44.00 PAYE per hour £39.50-£45.00 PAYE Inclusive of holiday pay per hour £40.50-£46.00 Umbrella Depending on skill...
-
Associate Director
3 hours ago
Cambridge, United Kingdom Brandon James Ltd Full timeAn international Quantity Surveying Consultancy is seeking a driven Associate Director, with a Quantity Surveyor / Employer's Agent background, for their growing Cambridge office. **The Associate Director Role** The Partners are seeking an Associate Director who is comfortable carrying out a dual Quantity Surveying and Employer's Agent role on an array of...
Associate Director, Clinical Operations
2 weeks ago
Parabilis Medicines, Inc is a biopharmaceutical company pioneering the discovery and development of Helicon™ peptide therapeutics; these ultra diverse alpha‑helical peptides are capable of efficient cell entry and modulation of both protein‑protein and protein‑DNA interactions. Through Helicon therapeutics, Parabilis is poised to revolutionize the medical possibilities for patients by precisely drugging intracellular targets long understood to be significant drivers of disease but never before drugged due to the limitations of existing drug modalities to act within the cell. FOG‑001, the company’s first‑in‑class TCF‑blocking β‑catenin inhibitor, is being evaluated in a Phase 1/2 study for patients with advanced solid tumors, including desmoid tumors and colorectal cancer. Parabilis is fully leveraging the unprecedented potential Helicons present by deploying proprietary, custom‑built machine learning and computational methods as part of its discovery and development process. Parabilis Medicines has raised more than $500 million to date from leading life sciences investors. Parabilis is headquartered in Cambridge, Mass. What’s the opportunity? In this role, you will help us develop a new drug modality for cancer and other diseases with unmet medical needs by working directly with Research and Development (R&D) functions to execute clinical trials. The Associate Director, Clinical Operations will provide expertise and oversight for multiple clinical trials or a clinical program to ensure the trials are conducted in accordance with the protocols, SOPs, GCP and departmental and corporate goals. This role will provide strategic leadership and direction to CROs and other vendors. Additionally, this leader will provide Clinical Operations expertise in cross‑functional meetings and corporate SOPs and initiatives. You will work in a nimble, dynamic, matrix environment with Clinical Trial Teams (CTT), investigative site staff and a variety of vendors and consultants to ensure trial delivery in accordance with SOPs, applicable regulations and guidelines. This individual will report directly to the Vice President, Clinical Operations. Accountable for delivery of assigned clinical program/trial budget, timelines, and resource management with focus on quality, including making recommendations and decisions regarding operational strategies to support trial and/or program objectives Develop operational strategy and clinical operations plans in support of execution of the Clinical Development Plan Lead and execute all trial phases based on stage of development in compliance with ICH/GCP, local regulations and Parabilis procedures Manage and provide oversight to the cross functional team and CRO/vendor(s) related to all aspects of clinical trial operations Evaluate, qualify, onboard and train vendors and investigative sites Review and provide clinical operations input into regulatory documents such as clinical trial protocols, informed consent forms (ICFs), investigator brochures, and study reports Perform and document study level Sponsor Oversight of outsourced clinical activities ensuring a trial storyboard is inspection ready Communicate study‑status, cost and issues to ensure timely decision‑making by senior management Oversee/collaborate on and contribute to inspection readiness activities that support audits and regulatory inspections related to clinical trial conduct Maintain oversight and participate in the creation/review/training/maintenance of departmental and organizational SOPs to ensure compliance Lead and/or participate in clinical operations workstreams related to departmental and operating model related initiatives Provide managerial oversight and mentorship to assigned clinical operations staff by providing clinical operations and functional area expertise and support identification and prioritization of study and program level work Conduct site and CRA oversight visits Drive trial and site level performance and engagement through regular communication, clear expectation setting, and development of action plans for issue remediation Develop and maintain strong relationships, including external partners such as investigators, site staff, collaborators and Key Opinion Leaders Program/trial budget management, reporting and forecasting activities Maintain current knowledge of external environment to ensure innovations (such as AI / Machine Learning) are considered and/or incorporated into clinical trial delivery strategy What you’ll need to be successful: B.S./B.A. in life science or related field 12+ years of clinical operations experience Experience in biotechnology, pharmaceutical and/or CRO industry Phase 1-3 global trial management experience, including first in human studies, preferably in Oncology Direct experience overseeing global CROs in both fully and partially outsourced models 3+ years of on‑site monitoring experience preferred Ability to guide study teams and to coordinate across multiple disciplines to achieve study goals and timelines Ability to motivate and inspire teams Awareness of drug supply chain Ability to work on complex or multiple projects and exercise critical thinking with minimal supervision Solid attention to detail and excellent organizational skills Strong interpersonal and communication skills (both written and oral) Supportive team member with a willingness and ability to fill functional gaps in a small but growing organization Ability to establish priorities, excellent sense of urgency and a strong desire to collaborate (self‑aware, effective relationship management and interpersonal skills) Creative problem‑solving skills Self‑motivated and adaptable in a dynamic, nimble, start‑up environment Strong computer skills and experience using Microsoft Office applications, CTMS, eTMF, IRT and EDC platforms Ability to work on‑site or remotely and attend in‑person meetings Willingness to travel (up to 30%) Core Values Growth‑Minded. We’re inventing a new class of medicines—one applicable to therapeutic targets that have been dreamt about, but always considered impossible to drug. Our work requires us to be curious, humble and adaptable. In(ter)dependent. We are fiercely independent as a leader indefying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options. Patient‑focused. We are deeply focused on patient outcomes, and all energy in the company is focused on science as it translates to patient impact. All‑In. We’re All‑In on solving some of the hardest scientific challenges and delivering one of the most effective new classes of drugs in history. The base salary range for this position is $160,000–$200,000 per year, depending on experience, qualifications, and internal practices. Parabilis’s total compensation package also includes an annual target bonus, equity, and a comprehensive suite of competitive benefits designed to support our employees’s overall well‑being. As an equal opportunity employer, Parabilis Medicines values an inclusive workplace and welcomes applicants of all backgrounds and experiences. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law. #J-18808-Ljbffr
