Postdoctoral Research Scientist In Cell Based High Throughput Screening

3 days ago


Oxford, United Kingdom University Of Oxford Full time

Centre for Medicines Discovery, NDM Research Building, Old Road Campus, Headington, Oxford, OX3 7FZ We have an exciting opportunity for a Postdoctoral Research Scientist in Cell-Based High Throughput Screening to join our research team at the Centre for Medicines Discovery, Nuffield Department of Medicine, to independently develop cellular assays relevant to cancer, then produce high throughput phenotypic screens using pooled CRISPR/Cas9 Functional Genomics and arrayed CRISPR libraries.
Reporting to the Head of Cellular Screening, you will work closely with other principal investigators in the TDI, Xcellomics, and the University of Oxford as well as with academic collaborators.
You will be responsible for independently developing and running various assays for target validation and CRISPR screening using multiple readouts including high-content imaging and plate-based readouts.
Various cell lines, iPS, or patient-derived cells will be used.
You will be leading projects, and taking responsibility for suggesting, constructing, and executing a project plan in conjunction with other members of the Cell Screening Facility/Xcellomics or collaborators.
You will be tasked with presenting the work of the TDI/Xcellomics to both internal and external audiences through conferences and manuscripts, providing facility tours, and providing educational outreach in collaboration with the NDM Outreach programs.
To be successful in this role, you will hold a PhD/DPhil (or close to completion) in cell-based functional genomic research techniques or another relevant subject.
You will have experience developing or using additional high throughput readouts including qPCR, FACS, and platereaders for cell-based assays.
Particular emphasis is on developing and validating cell-based assays and cell-based target validation assays.
You will be proficient in employing iPSC cell lines for validation of potential targets, including novel models or readouts.
You will have strong interpersonal skills and the ability to communicate technical information, both written and orally, in a readily understood manner, with colleagues at all levels as well as excellent communication skills.
You will also have the ability to write for publication, present research proposals and results, and represent the research group at meetings.



  • Oxford, Oxfordshire, United Kingdom ProImmune Full time

    Postdoctoral Research ScientistWe are seeking a highly skilled Postdoctoral Research Scientist to join our R&D team at ProImmune. As a key member of our team, you will play a crucial role in the development of new products and services.Key Responsibilities:Conduct research in protein biochemistry, molecular biology, and cell biologyDevelop and implement new...


  • Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    Biological Science Research OpportunityA highly competitive salary of £50,000 - £65,000 per annum is available for this Postdoctoral Research Scientist position in Oxford, United Kingdom.We are looking for a talented researcher to join our team at the University of Oxford's Department of Biology. As a Postdoctoral Research Scientist, you will be...


  • Oxford, United Kingdom CV-Library Full time

    An exciting opportunity is available for an R&D Scientist with expertise in Vector Development to join a growing start-up. With state-of-the-art facilities and a robust pipeline of upcoming projects, this role offers the chance to contribute to innovative research and development. Responsibilities: The purpose of this role is to develop mammalian plasmid...


  • Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    Job SummaryWe are seeking a highly skilled Postdoctoral Research Scientist to join our team at the University of Oxford. The successful candidate will play a key role in our ongoing research programme aimed at understanding the importance of epigenetic alterations in inflammatory bowel disease.About the RoleThis is a full-time, fixed-term position for up to...


  • Oxford, United Kingdom University of Oxford Full time

    We are seeking a Postdoctoral Scientist, the appointee will interact with clinicians as well as non-clinical scientists across the campus in Oxford, in the UK, and will collaborators with similar interests in Amsterdam, and elsewhere. The post arises as the latest element in an on-going research programme aimed at understanding the importance of...


  • Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    We are seeking an exceptional Postdoctoral Research Scientist to contribute to our pioneering research in cardiovascular medicine. The successful candidate will join our team of world-renowned experts in developing innovative treatments for inherited cardiomyopathy. Based within the esteemed University of Oxford Centre for Human Genetics, this fixed-term...


  • Oxford, Oxfordshire, United Kingdom Moderna Therapeutics Inc. Full time

    About the Role:Moderna Therapeutics Inc. is seeking a highly skilled Research Scientist in Cell Culture to join our team. As a key member of our Immuno-Assay development team, you will be responsible for supporting the running of cell-based Immuno-Assay development and qualification/validation to aid programs across multiple therapeutic areas.Your Key...

  • R&D Scientist

    2 days ago


    Oxford, United Kingdom Cranleigh Stem, Sustainability & Sheq Recruitment Full time

    An exciting opportunity is available for an R&D Scientist with expertise in Vector Development to join a growing start-up.With state-of-the-art facilities and a robust pipeline of upcoming projects, this role offers the chance to contribute to innovative research and development.Responsibilities: The purpose of this role is to develop mammalian plasmid...


  • Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    We are seeking a highly motivated Postdoctoral Research Scientist to join our team at the Sir William Dunn School of Pathology, University of Oxford. The successful candidate will support and analyse large bacterial genome collections to understand the epidemiology and evolution of antimicrobial resistance (AMR) in important pathogens.This is an exciting...

  • Senior Scientist I

    3 days ago


    Oxford, United Kingdom Caeruleus Full time

    Caeruleus is redefining the boundaries of precision medicine.Harnessing advanced machine learning and proprietary isoform sequencing technologies, we're pioneering a new era of therapeutic discovery beyond traditional gene expression analysis.Our revolutionary platform is transforming target discovery to develop medicines for millions of patients with unmet...


  • Oxford, United Kingdom Economic History Society Full time

    AN EXCITING OPPORTUNITY TO JOIN A MULTIDISCIPLINARY RESEARCH TEAM AT THE OXFORD CENTRE FOR NEUROINFLAMMATION You are invited to apply to join Professor Lars Fugger and his team at the University of Oxford, based at the Weatherall Institute of Molecular Medicine, John Radcliffe Hospital. You will join a team of research scientists, computational biologists,...

  • R&D Scientist

    4 days ago


    Oxford, United Kingdom Cranleigh STEM, Sustainability & SHEQ Recruitment Full time

    Job Description An exciting opportunity is available for an R&D Scientist with expertise in Vector Development to join a growing start-up. With state-of-the-art facilities and a robust pipeline of upcoming projects, this role offers the chance to contribute to innovative research and development. Responsibilities: The purpose of this role is to develop...

  • R&D Scientist

    4 days ago


    Oxford, United Kingdom Cranleigh STEM, Sustainability & SHEQ Recruitment Full time

    An exciting opportunity is available for an R&D Scientist with expertise in Vector Development to join a growing start-up. With state-of-the-art facilities and a robust pipeline of upcoming projects, this role offers the chance to contribute to innovative research and development.Responsibilities:The purpose of this role is to develop mammalian plasmid...

  • R&D Scientist

    1 day ago


    Oxford, United Kingdom Cranleigh STEM, Sustainability & SHEQ Recruitment Full time

    An exciting opportunity is available for an R&D Scientist with expertise in Vector Development to join a growing start-up. With state-of-the-art facilities and a robust pipeline of upcoming projects, this role offers the chance to contribute to innovative research and development.Responsibilities:The purpose of this role is to develop mammalian plasmid...

  • R&D Scientist

    5 days ago


    Oxford, United Kingdom Cranleigh STEM, Sustainability & SHEQ Recruitment Full time

    An exciting opportunity is available for an R&D Scientist with expertise in Vector Development to join a growing start-up. With state-of-the-art facilities and a robust pipeline of upcoming projects, this role offers the chance to contribute to innovative research and development.Responsibilities:The purpose of this role is to develop mammalian plasmid...

  • R&D Scientist

    4 days ago


    Oxford, United Kingdom Cranleigh STEM, Sustainability & SHEQ Recruitment Full time

    An exciting opportunity is available for an R&D Scientist with expertise in Vector Development to join a growing start-up. With state-of-the-art facilities and a robust pipeline of upcoming projects, this role offers the chance to contribute to innovative research and development.Responsibilities:The purpose of this role is to develop mammalian plasmid...


  • Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    Opportunity for a Postdoctoral ScientistThe University of Oxford is seeking a highly skilled Postdoctoral Scientist to join our research team.You will be working closely with clinicians and non-clinical scientists across the campus in Oxford, as well as collaborating with similar interests in Amsterdam and elsewhere.The post is part of an ongoing research...

  • R&D Scientist

    5 days ago


    Oxford, UK, Oxfordshire, United Kingdom Cranleigh STEM, Sustainability & SHEQ Recruitment Full time

    An exciting opportunity is available for an R&D Scientist with expertise in Vector Development to join a growing start-up. With state-of-the-art facilities and a robust pipeline of upcoming projects, this role offers the chance to contribute to innovative research and development.Responsibilities:The purpose of this role is to develop mammalian plasmid...


  • Oxford, United Kingdom University Of Oxford Full time

    We are seeking a Postdoctoral Research Associate in Mucosal immunology to join Professor Powrie's Mucosal Immunology Group.Professor Powrie is the Director of the Kennedy Institute of Rheumatology.You will join a dynamic and successful group studying immune regulation in the intestine and how this breaks down in inflammatory bowel disease and colorectal...


  • Oxford, Oxfordshire, United Kingdom Northreach Full time

    Immunotherapy Research LeaderWe are seeking a highly experienced Senior Scientist to lead our research efforts in immunotherapy development, specifically in the area of Chimeric Antigen Receptors (CARs) and T-Cell Receptors (TCRs).As a key member of our team, you will be responsible for designing and executing in vitro potency assays and functional assays to...