Senior Laboratory Research Scientist

2 weeks ago

Greater London, United Kingdom The Francis Crick Institute Full time
Senior Laboratory Research Scientist - Human Models Core

This is a full-time, permanent position on Crick terms and conditions of employment.

The Human Models Core (HMC) is an integral part of the Human Biology Facility. HMC comprises of scientific and technical staff from the Francis Crick Institute who provide a service and support to all researchers.

We are looking for a motivated, collaborative, scientist to work with HESCU /HMC staff, other STP scientist and the users to standardise reprogramming, QC and bank of PSC lines.

The post holder should embody and demonstrate our core Crick values: bold, open, and collegial.

Key responsibilities:

  • Reprogramming somatic cells to iPSCs.
  • Generation of iPSC derived organoids and other models.
  • Working and collaborating with scientist to develop scientific projects.
  • Provision of pluripotent stem cell culture suite, PSC QC and technical support to scientific groups within the Francis Crick Institute.
  • Teaching and training scientists in the best practice skillsets necessary to grow, characterise, differentiate and bank human PSC.
  • Support PSC genome editing unit, where needed.
  • Provision of support for the day-to-day running of the facility including but not limited to housekeeping, equipment maintenance.
  • Maintenance of databases and records for the unit.
  • Monitoring and communication status of projects.
  • Budget management.

Qualifications, experience and competencies:

  • PhD (or equivalent) in cell biology, stem cells, genetics or a relevant scientific discipline.
  • Substantial experience in reprogramming cells to pluripotency.
  • Extensive experience with quality control of PSC and related experience in a range of molecular biology techniques flow cytometry.
  • Experience in human organoid culture techniques.
  • Strong communication skills to audiences of varied expertise.
  • Proven track record of laboratory managerial and leadership skills.
  • Excellent organizational and time management skills.
  • Experience in facilitating collaborations.
  • Ability to teach and demonstrate techniques to other scientific staff.
  • Excellent organisational skills and record keeping with attention to detail.
  • Highly self-motivated with a pro-active approach.
  • Proven ability to work both collaboratively and independently.
  • Proven ability to drive projects and proficient in project management.

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