Research Scientist

4 weeks ago


Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full time

We are seeking a highly motivated and independent postdoctoral researcher to join our vibrant and interactive research group at the University of Cambridge.

The successful candidate will be responsible for designing and conducting high-throughput CRISPR screens in human tissue culture cells to explore sensitivity/resistance mechanisms to ionising radiation (IR).

From these studies, the postholder will establish how defects and deregulation of certain DNA damage response (DDR) and other cellular processes affect sensitivity and resistance to IR; and identify the potential clinical relevance of these effects in cancer.

The work will be multi-disciplinary, combining recently established genome engineering and genetic screening approaches in human cells with next-generation sequencing, bioinformatics, cell biology, molecular biology and biochemistry.

The ideal candidate will have a PhD in biological sciences or be close to completing their postgraduate degree, with strong experience in mammalian cell biology and a background in DNA damage/repair as well as an understanding of CRISPR-Cas9 technology.

The position offers a competitive salary and the opportunity to work in a diverse, vibrant and highly supportive research environment.

The successful candidate will be appointed as a grade 7 (£36,024 - £44,263 dependent on experience) and will be required to undergo a basic disclosure (criminal records check) check and a security check.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.


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