Senior Scientist

4 weeks ago


Cambridge, Cambridgeshire, United Kingdom Regeneron Pharmaceuticals, Inc Full time

We are seeking a highly skilled and passionate Senior Scientist to support Regeneron Cell Medicine's mission to bring innovative cell therapy products to patients.

This role will be critical to advance TCR- and CAR-based programs, as well as bring new ideas to improve our platforms and future programs.

Key Responsibilities:

  • Leverage molecular biology techniques to design constructs, clone, and generate lentiviral vectors using proprietary platform technology.
  • Design and carry out experimental plans to functionally characterize TCR- and CAR-based T cell products through cell-based assays and other relevant procedures.
  • Maintain detailed and timely records of experimental protocols, results, and observations.
  • Identify experimental challenges and collaborate with the team to troubleshoot technical issues and propose creative solutions.
  • Stay informed about the latest scientific advancements and apply relevant technologies to improve experimental processes.

Requirements:

  • Ph.D. in Immunology, Cancer Biology, Molecular Biology, or a related field.
  • 0-3 years of relevant experience or a BS/MS and 8-10+ years of relevant experience.
  • Hands-on experience with LV-vector construct design, cloning, vector production, and mastery of basic molecular biology techniques.
  • Experience with cell-based assays and functional assays measuring T cell activation, cytokine release, proliferation, survival, and tumor cell killing.

Preferred Qualifications:

  • Experience with standard readouts of tumor coculture (e.g. MSD, Luminex, ELISA, etc.).
  • Knowledge of standard TCR/CAR-T cells culture technique.
  • Experience developing and applying complex flow cytometry panels for the characterization of TCR/CAR-T cells.
  • Experience contributing to writing of patents and/or regulatory documents.

  • Senior Scientist

    4 weeks ago


    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Job Title: Senior ScientistJob Description:We are seeking a highly skilled Senior Scientist to join our team at Singular: Building Brilliant Biotechs. As a Senior Scientist, you will be responsible for leading the development of novel nanoparticle formulations for gene therapy applications.Key Responsibilities:Design and develop nanoparticles for drug...

  • Senior RNA Scientist

    1 month ago


    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Senior RNA Scientist // Drug Delivery // Nanoparticle // CambridgeYou are a project leading RNA scientist with a deep understanding of nucleic acid chemistry, RNA drug delivery, formulations, and RNA therapeutics.Our team is working with a rapidly growing biotech based in Cambridge that has developed unique polymer nanotechnology to encapsulate and release...

  • Senior Scientist

    3 days ago


    Cambridge, Cambridgeshire, United Kingdom Revvity Full time

    Job TitleSenior Scientist 2Job OverviewRevvity is a developer and provider of end-to-end solutions designed to help scientists, researchers, and clinicians solve the world's greatest health challenges. We pair the enthusiasm of an industry disruptor with the experience of a longtime leader. Our diverse team of 11,000+ colleagues from around the globe are...


  • Cambridge, Cambridgeshire, United Kingdom Amazon Full time

    Amazon is looking for a Senior Research Scientist to join our team and contribute to the development of innovative machine learning solutions.About the JobWe are seeking a highly skilled and experienced scientist with a strong background in machine learning and natural language processing to lead the development of new features and capabilities in our...


  • Cambridge, Cambridgeshire, United Kingdom Bionow Full time

    CK Group - Research Scientist / Senior ScientistJob Title: Research Scientist / Senior ScientistCategory: Technical rolesWe are seeking an experienced molecular biologist to join the Protein Engineering group at our research facility on Granta Park, Cambridge, UK.This is an exceptional opportunity to participate in pioneering science with an Industry-leading...


  • Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Job Title: Senior Research Scientist IJob Summary: We are seeking an experienced Senior Research Scientist I to join our team at Singular: Building Brilliant Biotechs. As a Senior Research Scientist I, you will be responsible for leading formulations science projects with a focus on gene therapy and nanoparticle design.Key Responsibilities:* Design and...


  • Cambridge, Cambridgeshire, United Kingdom https:www.energyjobline.comsitemap Full time

    Job Title: Research Scientist/Senior ScientistNxera Pharma, a technology powered biopharma company, is seeking an experienced molecular biologist to join their Protein Engineering group at their research facility on Granta Park, Cambridge, UK.The successful candidate will work closely with a diverse group of scientists to advance projects and facilitate GPCR...

  • Senior Scientist

    4 days ago


    Cambridge, Cambridgeshire, United Kingdom Newton Colmore Consulting Full time

    New opportunities have arisen at Newton Colmore Consulting for a talented Senior Scientist. As part of our Technology Development team, you will be responsible for developing cutting-edge technologies and solutions for the life sciences industry.As a Senior Scientist, you will have a strong background in molecular biology, biochemistry, or a related field....


  • Cambridge, Cambridgeshire, United Kingdom Abcam Full time

    Unlock the Power of GenomicsAre you a motivated and detail-oriented individual with a passion for genomics? We have an exciting opportunity for a Senior Research Scientist to join our Cell Engineering team at Abcam.About the RoleThis is a unique chance to work at the forefront of genomics, contributing to the development of cutting-edge technologies and...


  • Cambridge, Cambridgeshire, United Kingdom Evi Technologies Limited Full time

    Job Title: Senior Applied ScientistWe are seeking a highly skilled Senior Applied Scientist to join our team at Evi Technologies Limited. As a key member of our research team, you will be responsible for developing novel algorithms and modeling techniques to drive the state-of-the-art in speech and vocal arts synthesis.Key Responsibilities:Design, develop,...


  • Cambridge, Cambridgeshire, United Kingdom NHS Full time

    Exciting Opportunity for Senior ScientistWe are seeking a highly skilled and motivated Senior Scientist to join our team at the Cambridge Cellular Therapy Laboratory (CCTL). As a Senior Scientist, you will play a key role in developing and implementing cutting-edge cellular therapies, working closely with a team of world-class experts.The successful...


  • Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    We are seeking a highly skilled Senior Research Scientist to join our innovative team at Singular: Building Brilliant Biotechs. This role involves designing and executing experiments to support the development and validation of formulations, and analytical chemistry within our state-of-the-art labs.As a Senior Research Scientist, you will utilize your...


  • Cambridge, Cambridgeshire, United Kingdom Intertek Full time

    At Intertek, we are seeking a highly skilled Senior Analytical Scientist to join our cGMP labs in the UK. As a key member of our team, you will be responsible for providing full analytical testing support for pharmaceutical and biopharmaceutical products.Key Responsibilities:Undertake quantitative measurement of pharmaceutical compounds in various...


  • Cambridge, Cambridgeshire, United Kingdom Hyper Recruitment Solutions LTD Full time

    Job Title: Senior Research Scientist - Microbiology ExpertJob Summary:We are seeking a highly skilled Senior Research Scientist - Microbiology Expert to join our pre-clinical development team at a leading biopharmaceutical company based in the Cambridgeshire area. As a Senior Research Scientist - Microbiology Expert, you will be responsible for contributing...


  • Cambridge, Cambridgeshire, United Kingdom Revvity Full time

    Job TitleSenior Scientist 2About UsRevvity is a developer and provider of end-to-end solutions designed to help scientists, researchers, and clinicians solve the world's greatest health challenges. Our diverse team of 11,000+ colleagues from around the globe are vital to our success and the reason we're able to push boundaries in pursuit of better human...

  • Senior DMPK Scientist

    4 weeks ago


    Cambridge, Cambridgeshire, United Kingdom SRG Full time

    Job SummaryThe successful candidate will be a highly skilled Senior DMPK Scientist with a strong background in Pharmacokinetics and Pharmacodynamics. They will be responsible for leading a team of scientists in the development of new drugs and will have a deep understanding of the DMPK process.Key ResponsibilitiesDevelop and implement innovative PKPD...


  • Cambridge, Cambridgeshire, United Kingdom Flagship Pioneering Full time

    Job Title: Senior Healthcare ScientistAbout the Role:We are seeking a highly skilled Senior Healthcare Scientist to join our team at Flagship Pioneering. As a Senior Healthcare Scientist, you will be responsible for developing and applying bioinformatics, computational biology, and machine learning tools to generate insights and hypotheses from...


  • Cambridge, Cambridgeshire, United Kingdom jobrxiv - jobboard Full time

    About the RoleWe are seeking an ambitious and computationally skilled scientist to join our team at the Brain Architecture Project as a Senior Computational Scientist.Job OverviewThis is a unique opportunity to work with a world-renowned biomedical research institution in New York, shaping contemporary biomedical research and contributing to the home of...


  • Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full time

    The University of Cambridge, a world-renowned institution, is seeking an exceptional Senior HSC Research Scientist to join its esteemed Department of Haematology and Cambridge Stem Cell Institute.

  • Senior DMPK Scientist

    3 weeks ago


    Cambridge, Cambridgeshire, United Kingdom SRG Full time £76,000

    Job Title: Senior DMPK ScientistOverview:We are seeking an experienced Senior DMPK Scientist to join our Medicinal Chemistry and DMPK group. The successful candidate will have a strong background in drug metabolism and pharmacokinetics, with expertise in PKPD modelling and simulation.Key Responsibilities:Lead innovative experimental science projects:...