DMPK Project Lead

4 weeks ago

Slough, Slough, United Kingdom Lifelancer Full time
Job Title: DMPK Project Lead

We are seeking a highly skilled DMPK Project Lead to join our team at Lifelancer. As a key member of our research and development organization, you will be responsible for leading projects from early discovery to clinical phases, with a focus on nonclinical DMPK activities.

Key Responsibilities:
  • Design and execute experimental studies to support project goals and deliver data to internal and regulatory stakeholders.
  • Develop and maintain a deep understanding of preclinical pharmacokinetics, toxicokinetics, and related disciplines.
  • Apply your expertise to inform the design of new compounds and resolve ADME challenges.
  • Collaborate with project and development sciences colleagues to ensure successful project outcomes.
  • Stay up-to-date with the latest DMPK science and champion innovative approaches to project support.
  • Prepare DMPK sections of internal and regulatory documents, including IND, IMPD, IB, and NDA submissions.
  • Contribute to research aligned with our portfolio and publish papers in internationally recognized journals.
  • Provide scientific mentorship to junior staff.
Requirements:
  • PhD in Pharmaceutics, Pharmacology, Drug Metabolism, or Pharmacokinetics, with 7 years of postdoctoral industrial experience, or a related degree with 10 years of industrial experience in DMPK science.
  • Comprehensive understanding of discovery and development DMPK, including modeling and simulation.
  • Wide experience in pharmaceutical R&D, including knowledge of regulatory requirements and experience working with regulatory agencies.
  • Recognized track record of experience in DMPK/ADME and excellent knowledge in ADME/Enzymology/Drug Transporters.
  • Proven skills in in-depth mechanistic understanding of DMPK-related issues and translation to humans.
  • Knowledge of the drug development process in the Pharma Industry environment.

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