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DMPK Project Lead

2 months ago

Slough, Slough, United Kingdom Lifelancer Full time
Job Title: DMPK Project Lead

We are seeking a highly skilled DMPK Project Lead to join our team at Lifelancer. As a key member of our research organization, you will be responsible for leading projects from early discovery to candidate selection and into clinical phases.

Key Responsibilities:
  • Design and execute experimental studies to deliver data and interpretations to support project goals.
  • Collaborate with cross-functional teams to ensure project success and regulatory compliance.
  • Apply expertise in preclinical pharmacokinetics and related disciplines to inform project decisions.
  • Work with project teams to resolve ADME challenges and mitigate risks.
  • Champion innovative approaches to project support and stay at the forefront of DMPK science.
  • Prepare DMPK sections of internal and regulatory documents.
  • Participate in research aligned to DMPK and UCB's portfolio to publish research papers.
  • Provide scientific mentorship to junior staff.
Requirements:
  • PhD in Pharmaceutics, Pharmacology, Drug Metabolism, or Pharmacokinetics with 7 years of postdoctoral industrial experience, or a related degree with 10 years of industrial experience in DMPK science.
  • Comprehensive understanding of discovery and development DMPK, including modeling and simulation.
  • Wide experience in pharmaceutical R&D, including knowledge of regulatory requirements and experience working with regulatory agencies.
  • Recognized track record of experience in DMPK/ADME and excellent knowledge in ADME/Enzymology/Drug Transporters.
  • Proven track record of leading and hands-on experience of drug metabolism and pharmacokinetics studies.
  • Understanding of PKPD and preferably an understanding of PBPK modeling.
  • Proven skills for in-depth mechanistic understanding of DMPK-related issues.
  • Knowledge of the drug development processes in the Pharma Industry environment.

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