Research Scientist

3 weeks ago

Central London, United Kingdom The Francis Crick Institute Full time

The Francis Crick Institute is seeking a Senior Laboratory Research Scientist to investigate spatio-temporal control of cell division and cell cycle remodelling during cellular differentiation using 2D and 3D stem cell-based models of human gastrulation.

As part of the Quantitative Stem Cell Biology lab, headed by Dr Silvia Santos, you will drive a research project and contribute to collaborative projects within the lab. You will benefit from excellent mentorship and training and a vibrant and collegial scientific community within the Santos lab and at the Francis Crick Institute.

The lab's primary focus is understanding cell decision-making. Current areas of research include understanding regulatory mechanism regulating cell fate specification, cell cycle remodeling during cellular differentiation and the interplay between metabolism, cell cycle and cell fate. There is a strong focus on single cell analysis and advanced live cell imaging.

The team is multi-disciplinary, diverse and currently composed of three PhD students, two post-doctoral fellows and one principal laboratory research scientist. The Santos lab promotes independent and creative thinking and all members are committed to providing excellent training and mentorship.

Key Responsibilities
  • Lead specific research project under the Group Leader's supervision
  • Participate in collaborative projects
  • Attend and participate in group meetings and key Crick seminars
  • Keep accurate records of all work carried out
  • Train more junior colleagues when appropriate
  • Contribute to the preparation of scientific manuscripts
  • Contribute to the lab hESC feeding rota
  • Contribute to the collegial, positive and motivating lab atmosphere
Required Skills and Qualifications
  • PhD in any area relevant to the Life Sciences
  • Extensive experience in Molecular Biology
  • Extensive issue culture experience
  • Experience with imaging/microscopy
  • Experience and/or motivation to understand cell division in the context development and/or disease
  • Excellent organisational skills including impeccable recording of lab work
  • Strong communication skills
  • Very good interpersonal skills enabling the postholder to build effective collaborations with colleagues
  • Track record of working independently (e.g. contributing to a publication)
About the Role

This is a full-time, 1 year fixed term position on Crick terms and conditions of employment. We offer an estimated salary of £50,000-£65,000 per annum, depending on experience.

At the Francis Crick Institute, we conduct research at the forefront of biomedical research. We combine rigour with an open and collaborative culture, and are outward-looking, reflecting our status as a partnership of six organisations aiming to pool knowledge, ideas and resources.

We have a wide research portfolio with no divisions or departments, bringing biomedical researchers together with clinicians, physical scientists and applied scientists from our pharmaceutical partners.

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