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Genetics Specialist, Translational Genomics and Precision Medicine
1 month ago
We are seeking a highly skilled and motivated Specialist in Genetics to join our team in London, to implement cutting-edge human genetics approaches to answer questions that will support genetics driven precision medicine across our therapeutic areas of interest (including Type 2 Diabetes, Obesity, cardiovascular disease, and rare endocrine and blood disorders) and improve clinical trial success.
In this role, you will:
- Design, execute and interpret genetics studies using large-scale genetics data from biobanks, clinical trials, and integration with other omics – to predict disease risk, understand disease pathways, and stratify patient populations.
- Contribute to the exploration of cutting-edge genetic technologies and methodologies to advance translational genomics and precision medicine efforts.
- Apply genetic methodologies to support the clinical development of novel therapeutic targets, identify populations that will respond best to the treatments developed by our scientists, and drive the identification of predictive and prognostic biomarkers essential for patient stratification and treatment efficacy optimization.
- Collaborate with cross-functional teams to integrate genetic insights into the development of novel treatments and therapeutic approaches.
- Communicate genetic insights effectively and provide leadership in translating genetic findings into actionable strategies.
The Human Genetics Centre of Excellence (CoE) is part of a collaborative endeavour where you will work alongside statistical geneticists, clinicians, and computational and laboratory scientists from across the organisation, and with external collaborators, to help get the right treatment to the right patient.
We are searching for a self-driven scientist who works well in interdisciplinary teams. The ideal candidate holds a Ph.D. in human genetics, statistical genetics, bioinformatics or other related fields, with at least a few years of relevant industry or postdoctoral experience.
Familiarity with high performance computing and cloud-based computing environments is a plus. A strong interest in AI methods, and experience with machine learning techniques applied to genomics data is highly desired.
You should have:
- Familiarity with databases that house genomics data (including but not limited to UK Biobank, All of Us, Genomics England, gnomAD, TOPmed). Hands on experience is strongly preferred.
- Strong knowledge of genetics, genomics, and interest in the application of AI techniques in these fields.
- Proven track record by publications in peer-reviewed journals and/or conference presentations.
- Proficiency in programming languages, for analysis of large-scale datasets, e.g., R, Python, or similar, as well as experience with bioinformatics tools and databases.
- Have experience of communicating insights and presenting complex scientific concepts to a diverse audience.
Preferred experience includes:
- Experience with population stratification, Mendelian randomization, polygenic risk score (PRS) analysis, and/or gene-environment interaction analysis is strongly preferred.
- Understanding of multi-omics data (transcriptomic, proteomic, epigenomic etc.). Hands on experience is strongly preferred.
- Experience with biomarker discovery.
We want you to be your best self, so you'll have access to an award-winning Wellness programme, including Private Medical Insurance. Our culture is one of care, support and respect for our people. We are committed to making your workplace safe and believe that a transparent, inclusive culture and leadership is the way to empower every individual to do their very best.
We are an equal opportunities employer, and we commit to an inclusive recruitment process and equality of opportunity for all our job applicants. If you're a person with a disability, if you're neurodivergent, and need any adjustments to be made during the application and selection process, please send an email to akrw@novonordisk.com. Please include your name, the role you are interested in and the type of adjustment you need.
