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Senior Nucleic Acid Specialist
1 month ago
Transforming Genetic Medicine with Korro Bio
We are a pioneering biopharmaceutical company dedicated to developing innovative genetic medicines for rare and prevalent diseases. Our cutting-edge RNA editing platform enables us to harness the body's natural RNA editing process, delivering precise and transient single base edits.
About Us
- Korro Bio is generating a portfolio of differentiated programs designed to effect a precise yet transient single base edit.
- We are expanding the reach of genetic medicines by delivering additional precision and tunability.
Our Mission
We aim to redefine what's possible in genetic medicine and work towards making a lasting impact on human health.
Job Description: Senior Nucleic Acid Specialist - Oligonucleotide Compound Management
- Handling, characterization, automation, storage, and distribution of oligonucleotide compounds
- Work closely with a cross-functional team to advance our RNA editing drug discovery programs
- Quantifying, performing purity analysis via HPLC/LCMS, and documenting results
- Preparing samples and distributing information to downstream assay teams and pipelines
- Maintaining an organized physical and virtual lab, instrument qualification, and maintenance
Key Responsibilities:
- Oligonucleotide compound management and preparation of samples for biological screening
- Analysis and formulation of test articles for in vitro and in vivo studies
- Receiving, tracking, and maintaining physical and virtual inventory of test articles, formulations, and components
- Purity analysis via analytical HPLC and LCMS, ability to troubleshoot and develop methods on analytical systems
- Documentation, report generation, and presentation of results
Requirements:
- Master's degree with 2-5 years of experience in an industrial or academic laboratory setting or Bachelor's degree with 5-8+ years' experience
- Experience with nucleic acids and analytical chemistry with UV spectrophotometry, HPLC, and LCMS analysis
- High attention to detail with the ability to handle large sets of compounds accurately
- Good laboratory hygiene and extraordinary organizational skills
- Flexibility and self-motivation in a fast-paced work environment, ability to prioritize appropriately and meet deadlines
What We Offer: $80,000 - $110,000 per year, comprehensive benefits package, medical, dental, vision, 401(k) retirement plan, life insurance, and more.
