Scientific Officer

1 week ago

London, Greater London, United Kingdom Institute of Cancer Research (ICR) Full time

We are seeking a talented Scientific Officer to join our team at the Institute of Cancer Research (ICR). This exciting opportunity is part of our collaborative effort to advance cutting-edge research in structural and molecular biology.



In this role, you will provide essential technical expertise in developing methods and workflows in Correlative Light and Electron Microscopy (CLEM) and Cryo-Electron Tomography (cryoET) to target cellular processes for structural interrogation.



You will have the opportunity to work on a wide range of research projects, training and supporting researchers to ensure the effective application of these innovative methods.



Key Requirements


  • Expertise in the preparation of cells on grids via plunge freezing, or tissues by high pressure freezing for cryogenic imaging in a vitreous state.
  • Proven experience in operating advanced light and electron microscopy equipment.
  • Proven experience in cryogenic electron tomography (cryoET) and sub-tomographic averaging, including data collection, tomographic reconstruction and averaging.
  • Experience designing samples and projects using CLEM methods to enable in situ molecular reconstruction.
  • Ability to critically judge the quality/feasibility of cryoET and CLEM projects.
  • Ability to support researchers from different teams in their research projects through training and technical supervision/guidance.
  • Ability to work effectively with facility users, colleagues and contractors, including PhD students, research staff, collaborators, stores and facilities, engineers and visitors.


About the Institute of Cancer Research

The Institute of Cancer Research is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We are committed to supporting overseas applicants and welcome applications from all candidates, wherever in the world they are currently based.

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