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Clinical Research Laboratory Technician

1 month ago


Nottingham, Nottingham, United Kingdom Nottingham University Hospitals NHS Trusts Full time
About the Role

We are seeking an experienced Clinical Research Laboratory Technician to join our Research and Innovation department at Nottingham University Hospitals NHS Trusts. As a key member of our team, you will play a crucial role in the processing and quality control of cellular material for life-saving transplantation and other clinical research studies.

Key Responsibilities
  • Perform laboratory analyses and procedures associated with stem cell processing and cell therapy, including reporting results and maintaining accurate records.
  • Undertake flow cytometry and support the interpretation of results.
  • Store, deliver, and ship cells in accordance with regulatory guidelines.
  • Support quality control procedures and examine quality control results to identify areas for improvement.
  • Perform routine and complex laboratory-based work, including pre-analytical processing of clinical trial specimens and samples for analysis using various technologies.
  • Complete clerical tasks, including monitoring and querying sample processing requests, completing sample tracking logs, and maintaining equipment maintenance records.
  • Accurately follow and design protocols to ensure the smooth running of the facility and the accurate processing of study samples.
  • Collect, catalogue, and store human tissue, blood, and urine samples from within the R&I department, Nottingham University Hospitals, or external sites.
  • Organize sample retrieval from external sites, including some out-of-hours work.
  • Culture epithelial and smooth muscle cells from human lung biopsies.
  • Process human sputum samples, including differential cell count.
  • Record sample transfers accurately, both in and out of R&I laboratories.
  • Isolate stored samples for transfer to or from R&I laboratories, arranging couriers and ensuring samples are packed appropriately.
  • Observe all GLP, GCP, HSE, and HTA regulations, maintaining records to comply with the Human Tissue Act.
  • Maintain laboratory areas and equipment, ensuring adequate equipment maintenance and laboratory stock levels of chemicals and consumables.
  • Participate in the induction and training of new laboratory staff, providing mentorship and support within the clinical team.
  • Contribute to the development of clinical and research policies and Standard Operating Procedures.
  • Act as a resource for colleagues in relation to clinical studies.
  • Attend relevant training and gain experience from other laboratories, potentially involving travel.
  • Keep staff informed of the progress of clinical studies.
  • Maintain an up-to-date knowledge of relevant research-related articles, particularly those related to clinical studies.
  • Continuously develop professional skills according to regulatory guidance and current practice.
  • Assist with training placement students in relevant scientific techniques.
  • Attend national meetings and conferences related to clinical studies, as agreed with the R&I Laboratory Manager.
Requirements
  • BSc in a biological or biomedical subject or equivalent qualification or experience.
  • Extensive experience as a scientist/technician in an academic or healthcare/clinical laboratory within Haematology, Blood transfusion, and transplantation or other closely related fields.
  • Knowledge and experience of Good Laboratory Practice and research governance.
  • Demonstrated commitment to continuing education and training.
  • Ability to maintain confidentiality and act professionally.
  • Desirable qualifications include MSc in a biological or biomedical subject, IBMS membership, and experience with instrumentation, method development, and new technologies.
Working with Us

As a member of our Research and Innovation team, you will be part of a dynamic and collaborative environment that values innovation, excellence, and patient-centered care. We offer a range of benefits, including opportunities for professional development, a supportive team environment, and a commitment to work-life balance.