Clinical Research Laboratory Technician

4 weeks ago


Nottingham, Nottingham, United Kingdom Nottingham University Hospitals NHS Trusts Full time
About the Role

We are seeking an experienced Clinical Research Laboratory Technician to join our Research and Innovation department at Nottingham University Hospitals NHS Trust. As a key member of our team, you will play a crucial role in supporting the delivery of high-quality research and innovation services.

Key Responsibilities
  • Perform laboratory analyses and procedures associated with the post, including reporting results and maintaining records.
  • Undertake flow cytometry and support the interpretation of results.
  • Undertake storage, delivery, and shipping duties of cells.
  • Support quality control procedures and examine quality control results to identify poor performance.
  • Undertake routine and complex laboratory-based work, including the pre-analytical processing of clinical trial specimens and samples for analysis using various technologies.
  • Perform clerical tasks, including monitoring and querying sample processing requests made by the clinical team, completing sample tracking logs, equipment maintenance logs, and other documentations appropriate for the role.
  • Accurately follow or design protocols to ensure the smooth running of the facility and the accurate processing of study samples.
  • Collect, catalogue, and store human tissue, blood, and urine samples from within the R&I department, Nottingham University Hospitals, or external sites. Manage sample storage facilities and maintain collections, including monitoring freezers.
  • Organise sample retrieval from external sites, which may require flexibility in working hours.
  • Culture of epithelial and smooth muscle cells from human lung biopsies.
  • Process human sputum samples, including differential cell count.
  • Accurately record sample transfers both in and out of R&I laboratories.
  • Isolate stored samples for transfer to or from the R&I laboratories, arranging couriers and ensuring samples are packed appropriately.
  • Observe all GLP, GCP, HSE, and HTA regulations, maintaining records to comply with the Human Tissue Act, and adhering to Trust policy and procedures.
  • Be responsible for the upkeep of lab areas and equipment, maintaining laboratory stock levels of chemicals and consumables, and ensuring adequate equipment maintenance.
  • Maintain and clean laboratory equipment and maintain a high standard of housekeeping within the laboratory.
  • Assist in the induction and training of new laboratory staff, providing mentorship and support within the clinical team.
  • Contribute to the development of clinical and research policies and Standard Operating Procedures.
  • Act as a resource for colleagues in relation to clinical studies.
  • Attend relevant training and gain experience from other laboratories, which may involve travel.
  • Keep appropriate staff informed of the progress of clinical studies.
  • Maintain an up-to-date knowledge of relevant research-related articles, particularly those related to clinical studies.
  • Continue professional development according to appropriate regulatory guidance, keeping updated with current practice.
  • Assist with training of placement students in relevant scientific techniques.
  • Attend national meetings/conferences in relation to clinical studies as appropriate and agreed with the R&I Laboratory Manager.
Person Specification

Physical Skills

Essential

  • Manual dexterity required to perform tasks.
  • Physically capable of carrying out laboratory tasks and capable of intense periods of concentration.

Commitment to Trust Values and Behaviours

Essential

  • Must be able to demonstrate behaviours consistent with the Trust's behavioural standards.

Training & Qualifications

Essential

  • BSc in a biological or biomedical subject or attained or working towards NVQ level 3 in Clinical Laboratory Support or equivalent qualification or equivalent experience.
  • Extensive experience as a scientist/technician working in an academic or healthcare/clinical laboratory within Haematology, Blood transfusion, and transplantation or other closely related fields.
  • Knowledge and experience of Good Laboratory practice and research governance.
  • Demonstrates a commitment to continuing education and training.
  • Can maintain confidentiality and act professionally.

Desirable

  • MSc in a biological or biomedical subject.
  • IBMS membership.
  • Demonstrates a knowledge and awareness of instrumentation, method development, and new technologies.

Experience

Essential

  • Demonstrable knowledge/experience in flow cytometry and Tissue Culture work.
  • Relevant laboratory experience of at least 12 months.
  • Knowledge of Equal Opportunities, Human Tissue Act, and Data Protection/Confidentiality.
  • Knowledge of GCLP and Health & Safety legislations related to the Laboratory.
  • Conscientious and meticulous, demonstrates ability to organise their own work effectively.
  • Keyboard skills and computer literacy.

Desirable

  • HCPC Registration.
  • Experience of laboratory management and quality control.
  • Experience of laboratory stock control.
  • Training junior staff.
  • Has a genuine interest in the future of Stem Cell and Cell Therapy work.
  • Experience of audit.

Communication and Relationship Skills

Essential

  • Good interpersonal skills. Able to communicate concisely, effectively, and clearly.
  • Able to work well in a team and as an individual.
  • Can maintain confidentiality and act professionally.

Desirable

  • Demonstrates a range of IT skills.

Analytical and Judgement Skills

Essential

  • Able to make judgements regarding complex facts or situations that require analysis, interpretation, and comparison of a range of options. Trouble shooting & resolving issues such as mismatched samples, QA assessments, and technical failures.

Desirable

  • Experience of troubleshooting in a laboratory setting.

Planning and Organisation Skills

Essential

  • Able to plan own work activities and those of supervised staff.
  • Able to meet agreed targets on an ongoing basis.


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