Principal Biologist

1 week ago


Oxford, Oxfordshire, United Kingdom OMass Therapeutics Full time
About the Role

As a Senior Scientist at OMass Therapeutics, you will be part of a dynamic and innovative environment, driving groundbreaking research in structural biology. With a strong background in biochemistry, biophysics, or related fields, you will play a key role in advancing our mission to address patients' unmet needs.

We are seeking an experienced professional with a proven track record in single-particle cryo-electron microscopy and X-Ray crystallography. Your expertise will enable us to solve complex drug discovery challenges, working closely with interdisciplinary project teams.

**Responsibilities**

  • Perform X-ray crystallography experiments, including screen preparation, protein/ligand co-crystallization/soaking, and crystal harvesting.
  • Arrange crystal shipments and synchrotron time for remote data collection.
  • Process and analyze X-ray crystallography data, including indexing, integration, phasing, model building, and refinement.

**Requirements**

  • PhD or relevant experience in structural biology, biochemistry, biophysics, biotechnology, or equivalent.
  • Extensive practical experience in single-particle cryo-electron microscopy and X-Ray crystallography with a track record of successfully completed projects.
  • Excellent knowledge of structure determination with single-particle Cryo-EM, including sample preparation, data collection & processing, model building, and structural analysis.

**Benefits**

  • Competitive salary: £65,000 - £85,000 per annum.
  • Pension Scheme offering 6% employer contribution.
  • 25 days annual leave, plus bank holidays.


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