Senior Laboratory Research Scientist
1 month ago
The Francis Crick Institute is seeking a highly skilled Cryo-Electron Microscopy Specialist to support single-particle and tomography projects.
Key Responsibilities:
- Provide experimental or technical support to STP users.
- Contribute to management and maintenance of high-end cryo-electron microscopes.
- Support experimental design including sample preparation and imaging of biological specimens.
- Provide expertise and support in computational image analysis.
- Provide training in both experimental and computational aspects of cryo-EM.
Requirements:
- A higher degree in biological, physical, or engineering sciences; or equivalent relevant experience.
- Research experience and expertise in electron microscopy or a related technique.
- Specialist knowledge of cryo-electron microscope operation and high-resolution data collection.
- Experience in data analysis single particle images and/or tomography data.
- Experience with field emission gun microscopes and direct electron detectors.
- Proven track record in structural science.
- Excellent communication skills within a research environment, building highly effective working relationships with scientists and support staff.
Desirable:
- PhD in Structural Biology or related areas.
- Postdoctoral experience in conducting cutting-edge research in cryo-EM.
- Experience in the use of the cryo-FIB/SEM.
- Authorship in peer-reviewed publications in internationally recognized scientific journals.
- Specialist knowledge of cryo-EM reconstruction software.
- Knowledge of scientific computing including Unix shell scripting, Matlab, Python, programming languages.
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