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Senior Director of Pharmacology and Drug Metabolism

2 months ago


Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full time
About the Role

Bicycle Therapeutics is a clinical-stage biopharmaceutical company dedicated to developing innovative medicines for underserved diseases. As a Senior Director of Pharmacology and Drug Metabolism, you will play a crucial role in leading our team of scientists in the discovery and development of novel therapeutics.

Key Responsibilities
  • Provide scientific leadership in pharmacology and drug metabolism across all stages of our portfolio.
  • Oversee the quality and performance of all DMPK activities, including interactions with external CROs and internal project stakeholders.
  • Integrate data from multiple sources to inform our understanding of bicyclic peptide distribution, metabolism, and excretion.
  • Work closely with our discovery and regulatory teams to author and review DMPK-related IND documents.
  • Manage DMPK budgets for CROs and monitor their performance to ensure timely delivery of high-quality data.
Requirements
  • PhD in a relevant scientific discipline, such as drug metabolism, pharmacology, or pharmaceutical sciences.
  • Significant experience working on DMPK drug discovery and/or development projects with a track record of successful delivery.
  • Ability to adapt your working style to suit different cultures and partner expectations in both remote and office-based environments.
  • Nice-to-have: experience on radio-pharm projects.
What We Offer
  • A state-of-the-art campus environment with on-campus amenities.
  • A flexible working environment.
  • Competitive rewards, including an annual company bonus.
  • Employee recognition schemes.
  • 28 days annual leave, plus bank holidays and the option to buy up to 5 additional days annually.
  • Employer contribution to pension.
  • Life assurance cover 4x basic salary.
  • Private Medical Insurance, including optical and dental cover.
  • Enhanced parental leave policies.
  • Employee assistance program.
  • Health Cash Plan.
  • Access to company-subsidized gym membership.
  • Eligibility for an option grant to subscribe to shares in Bicycle Therapeutics plc.
About Us

Bicycle Therapeutics is committed to building a diverse workforce that reflects the communities we serve. We are an equal opportunities employer and welcome applications from all qualified candidates. Our company values include a strong commitment to innovation, collaboration, and excellence in all aspects of our work.