Senior Scientist: Molecular Assay Development Specialist

1 month ago


London, Greater London, United Kingdom ProtonDx Full time
Job Title: Senior Scientist: Molecular Assay Development

ProtonDx is a dynamic and innovative company that specializes in medical diagnostics and related technologies. With the recent launch of our regulatory-approved Point-of-Care Diagnostic product, Dragonfly, and a nucleic acid extraction kit for research use, SmartLid, we are poised for rapid growth and expansion into new product lines and strategic partnerships. Our mission is to push the boundaries of science and technology to improve healthcare outcomes.

Job Summary

We are seeking a highly experienced Senior Scientist to join our team in the design, development, and evaluation of molecular assays, particularly in the context of isothermal amplification chemistries, including LAMP. The successful candidate will have a strong background in molecular biology, biochemistry, or a related field, and will be responsible for developing and validating highly sensitive and specific in vitro molecular assays for the detection of pathogens associated with humans, animals, plants, and other areas.

Key Responsibilities
  • Develop and validate molecular assays for the detection of pathogens using LAMP and other isothermal amplification chemistries.
  • Conduct phylogenetic/genomic analysis to ensure the specificity and sensitivity of the designed molecular assays.
  • Contribute to scientific R&D projects through hands-on design, execution, and analysis of laboratory experiments.
  • Conduct regular in silico analysis and reporting of designed assays against evolving target pathogens.
  • Resolve complex technical challenges in line with clinical diagnostic assay requirements.
  • Accurately record and present scientific results through laboratory records, written reports, and presentations.
  • Prepare and QC master mixes and reagents for production of CE-marked and RUO products.
Requirements
  • PhD in a relevant life science discipline such as Microbiology, Genomics, Molecular Biology, or Biochemistry.
  • Significant experience (5+ years) in molecular assay development and optimization, particularly in the context of LAMP.
  • Experience in relevant laboratory techniques, including PCR, LAMP, and nucleic acid extraction and optimization.
  • Experience working to strict quality standards and in regulated environments.
  • A solid understanding of bioinformatics tools and methodologies.
  • Experience leading projects and independently delivering against agreed timescales and outputs.
  • An agile mind-set and excellent communication skills.
Reports to:

Head of Product Development & CSO



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