Director of Non-Clinical and Translational Research

6 days ago


Oxford, United Kingdom Blue Earth Diagnostics Full time

Role Overview

The Director – Nonclinical and Translational Science will be a key member of the Blue Earth Diagnostics Research & Development (R&D) team, providing technical expertise across all non-clinical and translational research activities.

Main Responsibilities

  • Define the strategy and drive the delivery of the nonclinical component of radiopharmaceutical R&D programmes.
  • Manage relationships with external parties such as academic collaborators and Contract Research Organisations (CROs).
  • Design and deliver rigorous scientific studies to generate key nonclinical proof of concept data and formal Good Laboratory Practice (GLP) toxicology programs for regulatory submissions.
  • Evaluate new in-licensing opportunities for Blue Earth's pipeline development through review of the nonclinical data packages.

Requirements

  • Educated to at least degree level, preferably with a PhD in the life sciences or equivalent research experience.
  • Background in research and development, in a pharma or biotech company (or CRO), preferably in early-stage drug development.
  • Experience in oncology is required, experience in neurology and cardiology is a plus.
  • Excellent understanding of cancer biology and recent developments in cancer diagnostics and therapy.
  • Experience of in vitro and in vivo pre-clinical tumour models, other pre-clinical models of disease pathology a plus.
  • Experience of delivering formal GLP-toxicology studies.
  • Experience of working in multi-functional R&D teams.
  • Ability to evaluate, interpret and synthesise scientific data, and verbally present and critically discuss scientific data at internal and external meetings.
  • Experience of outsourcing nonclinical work and/or establishing collaborative projects using contracts.
  • Good understanding of the drug development process and the regulatory environment.
  • Demonstrable project management and execution skills with experience of budget management.


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